Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.64 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CCR1 | P32246 | 4/20 | 0.39 |
| ▸ | CCR3 | P51677 | 4/20 | 0.39 |
| ▸ | HTR7 | P34969 | 3/20 | 0.39 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7465464 | 0.87 | MCHR1 (0.63) | MCHR1MAOBMAOADRD3KCNA3 | |
| SCHEMBL7459547 | 0.87 | MCHR1 (0.65) | MCHR1DRD3RAB9AADRA1A | |
| SCHEMBL7464781 | 0.86 | MCHR1 (0.73) | MCHR1KCNA3CCR1CCR3HTR7 | |
| SCHEMBL7466997 | 0.85 | MCHR1 (0.61) | MCHR1DRD3KCNA3CCR1CCR3 | |
| SCHEMBL7465382 | 0.83 | MCHR1 (0.62) | MCHR1DRD3HTR7ADRA1DADRA1A | |
| SCHEMBL7458838 | 0.83 | MCHR1 (0.65) | MCHR1DRD3RAB9AADRA1DADRA1A | |
| SCHEMBL7464932 | 0.83 | MCHR1 (0.62) | MCHR1DRD3KCNA3CCR3HTR7 | |
| SCHEMBL7462229 | 0.83 | MCHR1 (0.62) | MCHR1DRD3 | |
| SCHEMBL7470119 | 0.82 | MCHR1 (0.68) | MCHR1DRD3KCNA3CCR1CCR3 | |
| SCHEMBL7462164 | 0.82 | MCHR1 (0.62) | MCHR1DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1219294-A1 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2002-07-03 | — | — | EP | disclosed |