Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.33 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.33 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.33 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.33 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2885875 | 0.82 | SMN1; SMN2 (0.39) | PCSK9SMN1; SMN2AOC3ORAI1ORAI2 | |
| SCHEMBL5951659 | 0.75 | PCSK9 (0.46) | PCSK9POLBCTSKKDM4EALDH1A1 | |
| SCHEMBL2400555 | 0.72 | ORAI1 (0.40) | PCSK9SMN1; SMN2AOC3ORAI1ORAI2 | |
| SCHEMBL7796509 | 0.68 | MEN1 (0.42) | PCSK9ORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL7841888 | 0.68 | SLC6A4 (0.43) | PPARGPPARAPOLBKDM4ECA4 | |
| SCHEMBL907509 | 0.67 | TSHR (0.40) | PCSK9ORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL14779123 | 0.65 | SMN1; SMN2 (0.49) | SMN1; SMN2KDM4EALDH1A1CYP1A2HPGD | |
| SCHEMBL7469688 | 0.65 | ANPEP (0.38) | AOC3KDM4EMEN1TRPM2ALDH1A1 | |
| SCHEMBL13672306 | 0.65 | TSHR (0.44) | PPARGPPARAPOLBCTSKMEN1 | |
| SCHEMBL3289446 | 0.65 | PCSK9 (0.52) | PCSK9SMN1; SMN2KDM4EMEN1TRPM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1214306-A1 | LIQUID CRYSTAL COMPOUNDS | Qinetiq Limited (GB) | 2002-06-19 | — | — | EP | disclosed |
| WO-2001021606-A1 | LIQUID CRYSTAL COMPOUNDS | QINETIQ LIMITED (GB) | 2001-03-29 | — | — | WO | disclosed |