Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 2/20 | 0.38 |
| ▸ | LAP3 | P28838 | 1/20 | 0.38 |
| ▸ | LARS1 | Q9P2J5 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 4/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.33 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2400555 | 0.73 | ORAI1 (0.40) | CYP2D6ALDH1A1CYP3A4ALOX15TSHR | |
| SCHEMBL3848571 | 0.68 | ALDH1A1 (0.38) | MAOAALDH1A1CYP3A4ALOX15TSHR | |
| SCHEMBL2885875 | 0.68 | SMN1; SMN2 (0.39) | SIGMAR1ALDH1A1AOC3 | |
| SCHEMBL3463761 | 0.66 | ORAI1 (0.48) | MAOATAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7467180 | 0.65 | PCSK9 (0.37) | ALDH1A1CYP3A4ALOX15TSHRALOX12 | |
| SCHEMBL14947429 | 0.65 | TRPV6 (0.33) | ALDH1A1TSHR | |
| SCHEMBL12270868 | 0.65 | LARS1 (0.48) | ANPEPLAP3LARS1RNPEPDNPEP | |
| SCHEMBL30449778 | 0.65 | ANPEP (0.48) | ANPEPLAP3CYP2D6ALDH1A1CYP3A4 | |
| SCHEMBL30573729 | 0.65 | ANPEP (0.48) | ANPEPLAP3CYP2D6ALDH1A1CYP3A4 | |
| SCHEMBL30645239 | 0.64 | TSHR (0.50) | ANPEPLAP3CYP2D6ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1240169-A1 | PEPTIDE BETA-TURN MIMETIC COMPOUNDS AND PROCESSES FOR MAKING THEM | THE PROCTER & GAMBLE COMPANY (US) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001046197-A1 | PEPTIDE β-TURN MIMETIC COMPOUNDS AND PROCESSES FOR MAKING THEM | THE PROCTER & GAMBLE COMPANY (US) | 2001-06-28 | — | — | WO | disclosed |