Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 12/20 | 0.53 |
| ▸ | CNR2 | P34972 | 10/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GPR174 | Q9BXC1 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.41 |
| ▸ | GPR6 | P46095 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7471664 | 0.93 | CNR1 (0.55) | CNR1CNR2GPR174 | |
| SCHEMBL7458947 | 0.91 | CCR6 (0.46) | CNR1CNR2LMNA | |
| SCHEMBL7458931 | 0.84 | NSD2 (0.56) | CNR1CNR2ALDH1A1MAPTHTT | |
| SCHEMBL7463135 | 0.84 | CNR1 (0.53) | CNR1CNR2ALDH1A1MAPTLMNA | |
| SCHEMBL7468677 | 0.83 | ALDH1A1 (0.54) | ALDH1A1GAAMAPTHTTLMNA | |
| SCHEMBL7463150 | 0.83 | CYP1A2 (0.41) | CNR1CNR2ALDH1A1MAPTHTT | |
| SCHEMBL7464723 | 0.82 | PDGFRB (0.51) | MAPT | |
| SCHEMBL7464718 | 0.82 | CYP1A2 (0.37) | CNR1CNR2ALDH1A1GAAMAPT | |
| SCHEMBL7467225 | 0.82 | PAK1 (0.46) | ALDH1A1MAPTHTTLMNAKMT2A | |
| SCHEMBL7469276 | 0.78 | MAPT (0.41) | CNR1CNR2ALDH1A1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |