Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | ITGB1 | P05556 | 4/20 | 0.46 |
| ▸ | ITGA4 | P13612 | 4/20 | 0.46 |
| ▸ | CTSD | P07339 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7213313 | 0.93 | ITGB1 (0.52) | KMT2AITGB1ITGA4CTSDNPC1 | |
| SCHEMBL7467339 | 0.90 | KMT2A (0.45) | KMT2AITGB1ITGA4CTSDMEN1 | |
| SCHEMBL7461109 | 0.90 | KMT2A (0.45) | KMT2AITGB1ITGA4CTSDMEN1 | |
| SCHEMBL7460940 | 0.89 | ITGB1 (0.50) | ITGB1ITGA4CTSDCTSKALDH1A1 | |
| SCHEMBL7471442 | 0.89 | ITGB1 (0.50) | ITGB1ITGA4CTSDCTSKALDH1A1 | |
| SCHEMBL7468356 | 0.88 | KMT2A (0.45) | KMT2AITGB1ITGA4MEN1ALDH1A1 | |
| SCHEMBL7462016 | 0.86 | KMT2A (0.49) | KMT2AITGB1ITGA4MEN1ALDH1A1 | |
| SCHEMBL7468370 | 0.86 | KMT2A (0.49) | KMT2AITGB1ITGA4MEN1ALDH1A1 | |
| SCHEMBL7219807 | 0.86 | ITGB1 (0.54) | ITGB1ITGA4NPC1 | |
| SCHEMBL7461667 | 0.84 | ALDH1A1 (0.49) | KMT2AMEN1ALDH1A1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0805796-B1 | CELL ADHESION INHIBITORS | BIOGEN INC (US) | 2002-12-11 | — | — | EP | claimed |