Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 8/20 | 0.46 |
| ▸ | ABCC1 | P33527 | 7/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5869093 | 0.88 | ABCB1 (0.42) | ABCB1ABCC1MAPTL3MBTL1MAPK1 | |
| SCHEMBL7464046 | 0.81 | MAPT (0.49) | ABCB1ABCC1MAPTL3MBTL1MAPK1 | |
| SCHEMBL7698568 | 0.76 | ALDH1A1 (0.43) | ABCB1ABCC1MAPTL3MBTL1ALDH1A1 | |
| SCHEMBL25214665 | 0.76 | ABCC1 (0.55) | ABCB1ABCC1MAPTL3MBTL1MAPK1 | |
| SCHEMBL1266704 | 0.76 | KCNMA1 (0.62) | MAPTL3MBTL1MAPK1TDP1ALDH1A1 | |
| SCHEMBL1266702 | 0.76 | KCNMA1 (0.62) | MAPTL3MBTL1MAPK1TDP1ALDH1A1 | |
| SCHEMBL2369186 | 0.73 | ALDH1A1 (0.53) | MAPTL3MBTL1MAPK1TDP1ALDH1A1 | |
| SCHEMBL7467332 | 0.73 | ABCB1 (0.55) | ABCB1ABCC1MAPTALDH1A1KCNMA1 | |
| SCHEMBL7703599 | 0.71 | ABCB1 (0.44) | ABCB1ABCC1MAPTL3MBTL1MAPK1 | |
| SCHEMBL5869165 | 0.71 | MAPT (0.44) | ABCB1ABCC1MAPTL3MBTL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1224175-A2 | BENZODIAZEPINE DERIVATIVES AS METABOTROPIC GLUTAMATE RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2002-07-24 | — | — | EP | disclosed |
| WO-2001029012-A2 | BENZODIAZEPINE DERIVATIVES AS METABOTROPIC GLUTAMATE RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2001-04-26 | — | — | WO | disclosed |