Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | CRYZ | Q08257 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | HSPB1 | P04792 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10151441 | 0.84 | ALDH1A1 (0.45) | ALDH1A1HIF1ATP53HTTHSD17B10 | |
| SCHEMBL13174835 | 0.84 | ALDH1A1 (0.45) | ALDH1A1HIF1ATP53HTTHSD17B10 | |
| SCHEMBL2088798 | 0.84 | ALDH1A1 (0.51) | ALDH1A1HIF1ATP53HTTTSHR | |
| SCHEMBL7471531 | 0.83 | HSD17B10 (0.53) | ALDH1A1TP53HTTHSD17B10TSHR | |
| SCHEMBL10453217 | 0.83 | ALDH3A1 (0.48) | ALDH1A1HIF1ATP53HTTHSD17B10 | |
| SCHEMBL16583893 | 0.82 | MAPT (0.50) | ALDH1A1HIF1ATP53HTTCYP19A1 | |
| SCHEMBL7478286 | 0.82 | ALDH1A1 (0.45) | ALDH1A1TP53HTTCRYZKMT2A | |
| SCHEMBL7476827 | 0.81 | ALDH1A1 (0.51) | ALDH1A1TP53HTTHSD17B10TSHR | |
| SCHEMBL9984967 | 0.81 | HTT (0.61) | ALDH1A1HIF1ATP53HTTTSHR | |
| SCHEMBL993966 | 0.81 | POLB (0.44) | ALDH1A1HIF1ATP53HTTCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711768-B1 | BENZIMIDAZOLE DERIVATIVE | MITSUI CHEMICALS INC (JP) | 2002-02-13 | — | — | EP | disclosed |
| US-5852011-A | Benzimidazole derivatives | MITSUI CHEMICALS, INC. (JP) | 1998-12-22 | — | — | US | disclosed |
| EP-0711768-A1 | BENZIMIDAZOLE DERIVATIVE | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-15 | — | — | EP | disclosed |