Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 11/20 | 0.36 |
| ▸ | RAB9A | P51151 | 10/20 | 0.36 |
| ▸ | NPC1 | O15118 | 9/20 | 0.36 |
| ▸ | MEN1 | O00255 | 8/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.35 |
| ▸ | APBA1 | Q02410 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | TP53 | P04637 | 4/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7466456 | 0.94 | KMT2A (0.36) | KMT2ARAB9ANPC1MEN1CACNA1B | |
| SCHEMBL7468851 | 0.91 | MAPT (0.38) | KMT2ARAB9ANPC1MAPTTP53 | |
| SCHEMBL7468222 | 0.91 | NPC1 (0.37) | RAB9ANPC1MAPTSMN1; SMN2LMNA | |
| SCHEMBL7473460 | 0.89 | ABCB1 (0.35) | KMT2ARAB9ANPC1MEN1KDM4E | |
| SCHEMBL7472655 | 0.88 | PDGFRB (0.31) | KMT2AMEN1MAPTHSD17B10KDM4E | |
| SCHEMBL7464956 | 0.88 | KDM4E (0.35) | KMT2ARAB9ANPC1MEN1MAPT | |
| SCHEMBL7465517 | 0.88 | KDM4E (0.36) | KMT2ARAB9ANPC1MEN1MAPT | |
| SCHEMBL7459606 | 0.87 | ABL1 (0.32) | RAB9ANPC1KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL7475427 | 0.87 | KMT2A (0.33) | KMT2ARAB9ANPC1MEN1CACNA1B | |
| SCHEMBL6627433 | 0.87 | MAPT (0.38) | KMT2ARAB9ANPC1MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0656360-B1 | TRIFLUOROMETHYLPYRROLOINDOLE CARBOXYLIC ESTER DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | KYORIN SEIYAKU KK (JP) | 2002-11-20 | — | — | EP | disclosed |
| US-5629430-A | ANTICARCINOGENIC AGENTS | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0656360-A1 | TRIFLUOROMETHYLPYRROLOINDOLE CARBOXYLIC ESTER DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1995-06-07 | — | — | EP | disclosed |