Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 6/20 | 0.32 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.31 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.31 |
| ▸ | APBA1 | Q02410 | 3/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | PYGL | P06737 | 1/20 | 0.30 |
| ▸ | F11 | P03951 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6627433 | 0.92 | MAPT (0.38) | KMT2ARAB9ANPC1MMP2ABCB1 | |
| SCHEMBL7464956 | 0.89 | KDM4E (0.35) | KMT2ARAB9ANPC1TP53MEN1 | |
| SCHEMBL7465517 | 0.89 | KDM4E (0.36) | KMT2ARAB9ANPC1MMP2TP53 | |
| SCHEMBL7461868 | 0.88 | ABCB1 (0.32) | RAB9ANPC1ABCB1KDM4EPYGL | |
| SCHEMBL7473667 | 0.88 | PYGL (0.33) | ABCB1PYGLF11 | |
| SCHEMBL7473569 | 0.88 | P4HB (0.34) | ABCB1MAPTKDM4EF11 | |
| SCHEMBL7468851 | 0.88 | MAPT (0.38) | KMT2ARAB9ANPC1MMP2ABCB1 | |
| SCHEMBL7463040 | 0.87 | ADH1A (0.33) | — | |
| SCHEMBL7467710 | 0.87 | KMT2A (0.36) | KMT2ARAB9ANPC1CACNA1BAPBA1 | |
| SCHEMBL7471301 | 0.85 | CNR1 (0.31) | KMT2ANPC1MEN1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0656360-B1 | TRIFLUOROMETHYLPYRROLOINDOLE CARBOXYLIC ESTER DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | KYORIN SEIYAKU KK (JP) | 2002-11-20 | — | — | EP | disclosed |
| US-5629430-A | ANTICARCINOGENIC AGENTS | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0656360-A1 | TRIFLUOROMETHYLPYRROLOINDOLE CARBOXYLIC ESTER DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1995-06-07 | — | — | EP | disclosed |