Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7472169 | 0.91 | TSHR (0.53) | ALDH1A1MAPTMEN1KMT2ANPSR1 | |
| SCHEMBL5813680 | 0.88 | ALDH1A1 (0.58) | ALDH1A1MAPTMEN1KMT2ANPSR1 | |
| SCHEMBL7467742 | 0.85 | ALDH1A1 (0.55) | ALDH1A1MAPTMEN1KMT2ANPSR1 | |
| SCHEMBL11797889 | 0.82 | HTR7 (0.54) | ALDH1A1MAPTMEN1KMT2ANPSR1 | |
| SCHEMBL7465193 | 0.81 | MAPT (0.51) | ALDH1A1MAPTMEN1KMT2ATSHR | |
| SCHEMBL11681034 | 0.79 | ALDH1A1 (0.51) | ALDH1A1MAPTMEN1KMT2ANPSR1 | |
| SCHEMBL11792227 | 0.79 | ALDH1A1 (0.54) | ALDH1A1MAPTMEN1KMT2ANPSR1 | |
| SCHEMBL4828181 | 0.77 | MEN1 (0.55) | ALDH1A1MAPTMEN1KMT2ATSHR | |
| SCHEMBL11790769 | 0.77 | ALDH1A1 (0.52) | ALDH1A1MAPTMEN1KMT2ANPSR1 | |
| SCHEMBL10651901 | 0.76 | ALDH1A1 (0.57) | ALDH1A1MAPTMEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711768-B1 | BENZIMIDAZOLE DERIVATIVE | MITSUI CHEMICALS INC (JP) | 2002-02-13 | — | — | EP | disclosed |
| EP-0711768-A1 | BENZIMIDAZOLE DERIVATIVE | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-15 | — | — | EP | disclosed |
| US-4002631-A | HEAT-SENSITIVE COLOR FORMERS | HODOGAYA CHEMICAL CO., LTD. (JA) | 1977-01-11 | — | — | US | disclosed |