Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29740662 | 0.90 | MAPT (0.57) | MAPTALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL4912258 | 0.90 | MAPT (0.49) | MAPTALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL13292848 | 0.86 | MAPT (0.58) | MAPTALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL160430 | 0.86 | ALDH1A1 (0.57) | MAPTALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL12004712 | 0.83 | MAPT (0.55) | MAPTALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL3130705 | 0.83 | MAPT (0.51) | MAPTALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL7467722 | 0.81 | ALDH1A1 (0.51) | MAPTALDH1A1MEN1KMT2AATM | |
| SCHEMBL10490273 | 0.81 | ALDH1A1 (0.53) | MAPTALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL9651254 | 0.81 | MAPT (0.50) | MAPTALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL5172965 | 0.81 | MMP14 (0.51) | MAPTALDH1A1MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711768-B1 | BENZIMIDAZOLE DERIVATIVE | MITSUI CHEMICALS INC (JP) | 2002-02-13 | — | — | EP | disclosed |
| EP-0711768-A1 | BENZIMIDAZOLE DERIVATIVE | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-15 | — | — | EP | disclosed |