SCHEMBL4539723

SCHEMBL4539723

O=C1CN(c2ccc(O)cc2)C(=O)N1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 3/20 0.46
DDB1 Q16531 2/20 0.46
GAA P10253 4/20 0.43
KDM4E B2RXH2 3/20 0.43
TDP1 Q9NUW8 2/20 0.43
MAPT P10636 2/20 0.43
KMT2A Q03164 3/20 0.41
HSP90AA1 P07900 1/20 0.41
PKM P14618 1/20 0.41
MAPK1 P28482 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
MGLL Q99685 1/20 0.41
MEN1 O00255 2/20 0.38
CCNA2 P20248 1/20 0.38
CDK2 P24941 1/20 0.38
CCNA1 P78396 1/20 0.38
RAB9A P51151 2/20 0.38
NPC1 O15118 1/20 0.38
PDE3B Q13370 1/20 0.37
PDE3A Q14432 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8104104 0.82 CRBN (0.67) CRBNDDB1GAAKDM4ETDP1
SCHEMBL23142791 0.81 CRBN (0.71) CRBNDDB1KDM4ETDP1KMT2A
SCHEMBL10192194 0.80 MAPT (0.53) CRBNDDB1GAAKDM4ETDP1
SCHEMBL1421342 0.80 DDB1 (0.46) CRBNDDB1GAAKDM4ETDP1
SCHEMBL10813665 0.80 MEN1 (0.53) CRBNDDB1GAAKDM4ETDP1
SCHEMBL6245696 0.80 CRBN (0.46) CRBNDDB1GAAKDM4ETDP1
SCHEMBL7544193 0.79 ALDH1A1 (0.53) CRBNDDB1GAAKDM4ETDP1
SCHEMBL746783 0.79 CRBN (0.66) CRBNDDB1GAAKDM4ETDP1
SCHEMBL15707483 0.78 BCAT2 (0.46) CRBNDDB1GAAKDM4ETDP1
SCHEMBL8076294 0.78 DDB1 (0.47) CRBNDDB1GAAKDM4ETDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 307 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117816204-B Floating catalyst and application thereof in synthesizing p-hydroxy-phenylhydantoin TIANJIN VOCATIONAL INSTITUTE (CN) 2026-05-26 CN claimed
CN-119707825-A Crystal form of p-hydroxy phenylhydantoin and preparation method thereof 合肥菁科生物科技有限公司 2025-03-28 CN claimed
CN-119506370-A Preparation method of D-p-hydroxyphenylglycine 上海邦林生物科技有限公司 2025-02-25 CN claimed
CN-115927274-B Carbamoyl hydrolase mutants 上海邦林生物科技有限公司 2025-02-07 CN claimed
US-20250043323-A1 BIOCATALYSTS AND METHODS FOR THE SYNTHESIS OF PREGABALIN INTERMEDIATES Enzymaster (Ningbo) Bio-Engineering Co., Ltd (CN) 2025-02-06 US claimed
CN-119041202-B Antibacterial finishing agent, application method thereof and antibacterial pure cotton towel 淄博新亚纺织有限公司 2025-01-07 CN claimed
CN-119041202-A Antibacterial finishing agent, application method thereof and antibacterial pure cotton towel 淄博新亚纺织有限公司 2024-11-29 CN claimed
EP-4433602-A1 BIOCATALYSTS AND METHODS FOR THE SYNTHESIS OF PREGABALIN INTERMEDIATES Enzymaster (Ningbo) Bio-Engineering Co., Ltd. (CN) 2024-09-25 EP claimed
CN-118667895-A Improved production process of p-hydroxyphenylglycine by enzyme method 联邦制药(内蒙古)有限公司 2024-09-20 CN claimed
CN-118389483-A Preparation method and application of carrier-free precipitation crosslinking hybridization nanoflower co-immobilized double-enzyme catalyst 天津科技大学 2024-07-26 CN claimed
CN-106083629-A The preparation method of D-pHPG 安徽赛诺制药有限公司 2016-11-09 CN claimed
CN-105859629-A Production method for para hydroxybenzene 芜湖宝瓶智能化服务外包有限公司 2016-08-17 CN claimed
CN-104480099-A Method for immobilizing effective hydantoinase expression fungus LULIANG UNIVERSITY 2015-04-01 CN claimed
US-20020045238-A1 Thermostable D-hydantoinase and the application thereof NATIONAL SCIENCE COUNCIL (TW) 2002-04-18 US claimed
EP-0437058-B1 Formation of hydroxyaromatic ketoacetal from an hydroxyaromatic methylketone and production of 5-(4'-hydroxyphenyl)hydantoin and D-p-hydroxyphenylglycine from 4-hydroxyacetophenone HOECHST CELANESE CORP (US) 1995-12-27 EP claimed
US-5338859-A Reacting a hydantoin with a calcium base; crystallization; precipitation; separation HOECHST CELANESE CORPORATION (US) 1994-08-16 US claimed
US-5120855-A Formation of hydroxyaromatic ketoacetal from a hydroxyaromatic methylketone and production of 5-(4'-hydroxyphenyl)hydantoin and Dp-hydroxyphenylglycine from 4-hydroxyacetophenone HOECHST CELANESE CORPORATION (US) 1992-06-09 US claimed
EP-0437058-A1 Formation of hydroxyaromatic ketoacetal from an hydroxyaromatic methylketone and production of 5-(4'-hydroxyphenyl)hydantoin and D-p-hydroxyphenylglycine from 4-hydroxyacetophenone HOECHST CELANESE CORPORATION (US) 1991-07-17 EP claimed
EP-0078455-B1 A THERMOPLASTIC POLYESTER COMPOSITION POLYPLASTICS CO. LTD. (JP) 1986-02-19 EP claimed
US-4436877-A HYDANTOIN TO RETARD EVOLUTION OF AROMATIC DIACID VAPORS DURING MELT PROCESSING POLYPLASTICS CO., LTD. (JP) 1984-03-13 US claimed