Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 4/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2412200 | 0.83 | HDAC6 (0.32) | HDAC6HDAC1HDAC2 | |
| SCHEMBL2412201 | 0.83 | HDAC6 (0.32) | HDAC6HDAC1HDAC2 | |
| SCHEMBL2554210 | 0.80 | CTSK (0.30) | CTSK | |
| SCHEMBL1494389 | 0.79 | HDAC6 (0.34) | HDAC6HDAC1HDAC2 | |
| SCHEMBL8274243 | 0.78 | CTSK (0.34) | CTSKHDAC6HDAC1HDAC2 | |
| SCHEMBL5559416 | 0.78 | CTSK (0.34) | CTSKHDAC6HDAC1HDAC2 | |
| SCHEMBL4299159 | 0.78 | CTSK (0.34) | CTSKHDAC6HDAC1HDAC2 | |
| Hydrochloric Acid SCHEMBL14966370 | 0.78 | HDAC6 (0.33) | HDAC6HDAC1HDAC2 | |
| SCHEMBL2487152 | 0.74 | MEN1 (0.33) | HDAC6HDAC1HDAC2 | |
| SCHEMBL22364736 | 0.74 | CTSK (0.34) | CTSKHDAC6HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1073672-A1 | ANTIPICORNAVIRAL COMPOUNDS, THEIR PREPARATION AND USE | AGOURON PHARMACEUTICALS, INC. (US) | 2001-02-07 | — | — | EP | disclosed |
| WO-1999057135-A1 | ANTIPICORNAVIRAL COMPOUNDS, THEIR PREPARATION AND USE | AGOURON PHARMACEUTICALS, INC. (US) | 1999-11-11 | — | — | WO | disclosed |