Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2412200 | 1.00 | HDAC6 (0.32) | HDAC6HDAC1HDAC2 | |
| SCHEMBL7468074 | 0.83 | CTSK (0.33) | HDAC6HDAC1HDAC2 | |
| SCHEMBL1494389 | 0.78 | HDAC6 (0.34) | HDAC6HDAC1HDAC2 | |
| Hydrochloric Acid SCHEMBL14966370 | 0.76 | HDAC6 (0.33) | HDAC6HDAC1HDAC2 | |
| SCHEMBL2487152 | 0.73 | MEN1 (0.33) | HDAC6HDAC1HDAC2 | |
| SCHEMBL14842450 | 0.72 | HDAC6 (0.34) | HDAC6HDAC1HDAC2 | |
| SCHEMBL9038784 | 0.70 | AAK1 (0.36) | HDAC6HDAC1HDAC2 | |
| SCHEMBL16076753 | 0.70 | CA1 (0.32) | HDAC6HDAC1HDAC2 | |
| SCHEMBL30739107 | 0.70 | CA1 (0.32) | HDAC6HDAC1HDAC2 | |
| SCHEMBL28012697 | 0.70 | HDAC6 (0.33) | HDAC6HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011106627-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2011-09-01 | — | — | WO | disclosed |