Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | IKBKB | O14920 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MGAM | O43451 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | EIF4A1 | P60842 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10339542 | 0.78 | RAB9A (0.50) | HTTATMMAPTALDH1A1IKBKB | |
| SCHEMBL1682777 | 0.76 | RAB9A (0.55) | HTTATMMAPTALDH1A1RAB9A | |
| SCHEMBL8807038 | 0.75 | SMN1; SMN2 (0.56) | MAPTALDH1A1IKBKBRAB9ANPC1 | |
| SCHEMBL2011679 | 0.75 | KMT2A (0.50) | HTTATMMAPTALDH1A1IKBKB | |
| SCHEMBL14842175 | 0.75 | ALDH1A1 (0.49) | HTTATMMAPTALDH1A1RAB9A | |
| SCHEMBL14179218 | 0.75 | TDP1 (0.50) | MAPTALDH1A1RAB9ANPC1MEN1 | |
| SCHEMBL1369397 | 0.74 | KMT2A (0.53) | HTTATMMAPTALDH1A1RAB9A | |
| SCHEMBL352221 | 0.74 | IKBKB (0.51) | MAPTALDH1A1IKBKBRAB9ANPC1 | |
| SCHEMBL31133499 | 0.74 | IKBKB (0.51) | MAPTALDH1A1IKBKBRAB9ANPC1 | |
| SCHEMBL30034075 | 0.74 | ALDH1A1 (0.61) | MAPTALDH1A1IKBKBRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0326330-B1 | Quinoline fungicides | DOW AGROSCIENCES LLC (US) | 2002-07-24 | — | — | EP | disclosed |
| CN-1031263-C | Quinoline, quinazoline, and cinnoline | LILLY CO ELI (US) | 1996-03-13 | — | — | CN | disclosed |
| US-5296484-A | Applying fungicide to locus of plant pathogen | DOWELANCO (US) | 1994-03-22 | — | — | US | disclosed |
| US-5240940-A | Synergistic nmixture | DOWELANCO (US) | 1993-08-31 | — | — | US | disclosed |
| US-5145843-A | For plants | DOWELANCO (US) | 1992-09-08 | — | — | US | disclosed |
| CN-1034925-A | Quinoline, quinazoline and cinnoline | LILLY CO ELI (US) | 1989-08-23 | — | — | CN | disclosed |
| CN-1034924-A | quinoline, quinazoline and cinnoline derivatives | LILLY CO ELI (US) | 1989-08-23 | — | — | CN | disclosed |
| EP-0326328-A2 | Quinoline, quinazoline, and cinnoline derivatives | DowElanco (US) | 1989-08-02 | — | — | EP | disclosed |
| EP-0326330-A2 | Quinoline, quinazoline, and cinnoline fungicides | DowElanco (US) | 1989-08-02 | — | — | EP | disclosed |