Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.59 |
| ▸ | HTR1A | P08908 | 4/20 | 0.59 |
| ▸ | HTR2A | P28223 | 3/20 | 0.59 |
| ▸ | DRD3 | P35462 | 3/20 | 0.59 |
| ▸ | HTR7 | P34969 | 2/20 | 0.59 |
| ▸ | HRH1 | P35367 | 2/20 | 0.59 |
| ▸ | HTR2B | P41595 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.53 |
| ▸ | DRD1 | P21728 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8596935 | 0.87 | TSHR (0.61) | DRD2HTR1AHTR2ADRD3HTR7 | |
| Hydrochloric Acid SCHEMBL6984682 | 0.83 | DRD2 (0.58) | DRD2HTR1AHTR2ADRD3HTR7 | |
| SCHEMBL13904313 | 0.81 | DRD2 (0.65) | DRD2HTR1AHTR2ADRD3HTR7 | |
| SCHEMBL11541244 | 0.81 | DRD2 (0.65) | DRD2HTR1AHTR2ADRD3HTR7 | |
| Hydrochloric Acid SCHEMBL11545929 | 0.80 | DRD2 (0.63) | DRD2HTR1AHTR2ADRD3HTR7 | |
| Hydrochloric Acid SCHEMBL7457057 | 0.78 | SRD5A2 (0.42) | HTR1ASLC6A4SIGMAR1 | |
| SCHEMBL6234537 | 0.75 | DRD2 (0.77) | DRD2HTR1AHTR2ADRD3HTR7 | |
| SCHEMBL11834324 | 0.75 | TSHR (0.67) | DRD2HTR1AHTR2ADRD3HTR7 | |
| SCHEMBL11834858 | 0.75 | TSHR (0.67) | DRD2HTR1AHTR2ADRD3HTR7 | |
| SCHEMBL4496558 | 0.75 | TSHR (0.76) | DRD2HTR1AHTR2ADRD3HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0940401-B1 | 2-CARBONYLTHIAZOLE DERIVATIVES AND USE OF THE SAME | TAISHO PHARMACEUTICAL CO LTD (JP) | 2002-11-06 | — | — | EP | disclosed |
| US-6166033-A | 2-carbonylthiazole derivatives and use of the same | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2000-12-26 | — | — | US | disclosed |
| EP-0940401-A1 | 2-CARBONYLTHIAZOLE DERIVATIVES AND USE OF THE SAME | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1999-09-08 | — | — | EP | disclosed |