Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF3 | O95398 | 2/20 | 0.34 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7464607 | 0.93 | HSD17B10 (0.38) | RAPGEF3HSD17B10 | |
| SCHEMBL7460951 | 0.93 | RAPGEF3 (0.36) | RAPGEF3PTGER3HSD17B10ALDH1A1 | |
| SCHEMBL7463607 | 0.90 | KMT2A (0.37) | RAPGEF3HSD17B10ALDH1A1 | |
| SCHEMBL7460031 | 0.90 | KMT2A (0.37) | RAPGEF3ALDH1A1 | |
| SCHEMBL7458058 | 0.90 | RAPGEF3 (0.33) | RAPGEF3HSD17B10ALDH1A1 | |
| SCHEMBL7462646 | 0.90 | RAPGEF3 (0.36) | RAPGEF3PTGER3ALDH1A1 | |
| SCHEMBL7460241 | 0.89 | RAPGEF3 (0.34) | RAPGEF3PTGER3ALDH1A1 | |
| SCHEMBL7468910 | 0.89 | PTGER3 (0.35) | RAPGEF3PTGER3ALDH1A1PLA2G10 | |
| SCHEMBL7461643 | 0.88 | RAPGEF3 (0.37) | RAPGEF3ALDH1A1 | |
| SCHEMBL7460145 | 0.88 | MEN1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0908457-B1 | 3-(1,2-benzisothiazol- and isoxazol-5-Y1)-2,4(1H,3H)-pyrimidinedione or thione and 3-(1,2-benzisothiazol- and isoxazol-5-y1)-4(3H)-pyrimidinone or thione herbicidal agents | BASF AG (DE) | 2002-11-13 | — | — | EP | disclosed |
| EP-0908457-A1 | 3-(1,2-benzisothiazol- and isoxazol-5-Y1)-2,4(1H,3H)-pyrimidinedione or thione and 3-(1,2-benzisothiazol- and isoxazol-5-y1)-4(3H)-pyrimidinone or thione herbicidal agents | American Cyanamid Company (US) | 1999-04-14 | — | — | EP | disclosed |