Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER3 | P43115 | 3/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.34 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7462120 | 0.93 | HTR6 (0.34) | MAPTL3MBTL1 | |
| SCHEMBL7464601 | 0.93 | PTGER1 (0.33) | PTGER1MAPTL3MBTL1 | |
| SCHEMBL7460947 | 0.93 | L3MBTL1 (0.35) | PTGER3PTGER1L3MBTL1ALDH1A1RAPGEF3 | |
| SCHEMBL7463599 | 0.92 | L3MBTL1 (0.36) | L3MBTL1 | |
| SCHEMBL7460026 | 0.90 | KMT2A (0.37) | MAPTL3MBTL1ALDH1A1 | |
| SCHEMBL7458051 | 0.90 | L3MBTL1 (0.35) | PTGER1L3MBTL1ALDH1A1 | |
| SCHEMBL7460235 | 0.89 | PTGER3 (0.34) | PTGER3PLA2G10ALDH1A1RAPGEF3 | |
| SCHEMBL7468917 | 0.89 | RAPGEF3 (0.34) | PTGER3PLA2G10ALDH1A1RAPGEF3 | |
| SCHEMBL7462639 | 0.89 | EGFR (0.34) | PTGER3MAPTL3MBTL1ALDH1A1RAPGEF3 | |
| SCHEMBL7460136 | 0.88 | MEN1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0908457-B1 | 3-(1,2-benzisothiazol- and isoxazol-5-Y1)-2,4(1H,3H)-pyrimidinedione or thione and 3-(1,2-benzisothiazol- and isoxazol-5-y1)-4(3H)-pyrimidinone or thione herbicidal agents | BASF AG (DE) | 2002-11-13 | — | — | EP | disclosed |
| EP-0908457-A1 | 3-(1,2-benzisothiazol- and isoxazol-5-Y1)-2,4(1H,3H)-pyrimidinedione or thione and 3-(1,2-benzisothiazol- and isoxazol-5-y1)-4(3H)-pyrimidinone or thione herbicidal agents | American Cyanamid Company (US) | 1999-04-14 | — | — | EP | disclosed |