Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8991793 | 0.79 | MAPT (0.69) | L3MBTL1MAPTLMNAKMT2AALDH1A1 | |
| SCHEMBL7473099 | 0.71 | NAPRT (0.49) | NAPRTL3MBTL1LMNAKMT2AMEN1 | |
| SCHEMBL7465975 | 0.71 | NAPRT (0.49) | NAPRTL3MBTL1LMNAKMT2AMEN1 | |
| SCHEMBL103123 | 0.71 | RAB9A (0.61) | NAPRTL3MBTL1MAPTLMNAKMT2A | |
| SCHEMBL9180279 | 0.70 | CYP1B1 (0.64) | NAPRTMAPTLMNAKMT2AALDH1A1 | |
| SCHEMBL2306301 | 0.69 | RAB9A (0.76) | NAPRTL3MBTL1MAPTLMNAKMT2A | |
| SCHEMBL1553298 | 0.69 | CYP11B1 (0.50) | NAPRTL3MBTL1LMNAKMT2AALDH1A1 | |
| SCHEMBL12709046 | 0.69 | CYP11B1 (0.50) | NAPRTL3MBTL1LMNAKMT2AALDH1A1 | |
| SCHEMBL1553299 | 0.69 | CYP11B1 (0.50) | NAPRTL3MBTL1LMNAKMT2AALDH1A1 | |
| SCHEMBL25406665 | 0.68 | NAPRT (0.61) | NAPRTL3MBTL1MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077701-A4 | ANTI-VIRAL COMPOUNDS | LILLY CO ELI (US) | 2002-03-20 | — | — | EP | disclosed |
| EP-1077701-A1 | ANTI-VIRAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999059587-A1 | ANTI-VIRAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 1999-11-25 | — | — | WO | disclosed |