Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KCNQ3 | O43525 | 3/20 | 0.47 |
| ▸ | KCNQ2 | O43526 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MDM4 | O15151 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.40 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.40 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7465975 | 1.00 | NAPRT (0.49) | NAPRTL3MBTL1KCNQ3KCNQ2LMNA | |
| SCHEMBL7676637 | 0.79 | KMT2A (0.39) | NAPRTL3MBTL1KCNQ3KCNQ2MDM4 | |
| SCHEMBL7679465 | 0.79 | KMT2A (0.39) | NAPRTL3MBTL1KCNQ3KCNQ2MDM4 | |
| SCHEMBL2300680 | 0.74 | JAK2 (0.41) | GRM4 | |
| SCHEMBL3383611 | 0.72 | NAPRT (0.66) | NAPRTL3MBTL1KCNQ3KCNQ2LMNA | |
| SCHEMBL103123 | 0.72 | RAB9A (0.61) | NAPRTL3MBTL1KCNQ3KCNQ2LMNA | |
| SCHEMBL31473447 | 0.72 | NAPRT (0.66) | NAPRTL3MBTL1KCNQ3KCNQ2LMNA | |
| SCHEMBL7469065 | 0.71 | NAPRT (0.47) | NAPRTL3MBTL1KCNQ3KCNQ2LMNA | |
| SCHEMBL2301555 | 0.71 | CTNNB1 (0.57) | RAB9ANPC1 | |
| SCHEMBL12427655 | 0.71 | CTNNB1 (0.57) | RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077701-A4 | ANTI-VIRAL COMPOUNDS | LILLY CO ELI (US) | 2002-03-20 | — | — | EP | disclosed |
| US-6358971-B1 | FOR INHIBITING THE GROWTH OF A PICORNAVIRUS | ELI LILLY AND COMPANY | 2002-03-19 | — | — | US | disclosed |
| EP-1077701-A1 | ANTI-VIRAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999059587-A1 | ANTI-VIRAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 1999-11-25 | — | — | WO | disclosed |