Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 3/20 | 0.44 |
| ▸ | ADH1A | P07327 | 3/20 | 0.44 |
| ▸ | ADH7 | P40394 | 3/20 | 0.44 |
| ▸ | ADH1C | P00326 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.38 |
| ▸ | ADH4 | P08319 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9935804 | 0.91 | EPHX1 (0.50) | ADH1BADH1AADH7ADH1CTSHR | |
| SCHEMBL9936340 | 0.91 | EPHX1 (0.50) | ADH1BADH1AADH7ADH1CTSHR | |
| SCHEMBL2241713 | 0.80 | PTGS1 (0.35) | — | |
| SCHEMBL9936326 | 0.75 | — | — | |
| SCHEMBL10198685 | 0.75 | TSHR (0.52) | ADH1BADH1AADH7ADH1CTSHR | |
| SCHEMBL23136900 | 0.75 | KDM4E (0.35) | TSHRSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL4075807 | 0.75 | ADRA1A (0.37) | TSHRALDH1A1HDAC3HDAC1HDAC2 | |
| SCHEMBL13937213 | 0.71 | TSHR (0.48) | ADH1BADH1AADH7ADH1CTSHR | |
| SCHEMBL21553357 | 0.71 | TSHR (0.48) | ADH1BADH1AADH7ADH1CTSHR | |
| SCHEMBL15114076 | 0.71 | TSHR (0.48) | ADH1BADH1AADH7ADH1CTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2651876-B1 | POLYAMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS | SIKA TECH AG (CH) | 2017-08-09 | — | — | EP | claimed |
| US-8877955-B2 | Secondary aminosilanes | SIKA TECHNOLOGY AG (CH) | 2014-11-04 | — | — | US | claimed |
| US-20130281562-A1 | SECONDARY AMINOSILANES | SIKA TECHNOLOGY AG (CH) | 2013-10-24 | — | — | US | claimed |
| EP-2651876-A1 | POLYAMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS | Sika Technology AG (CH) | 2013-10-23 | — | — | EP | claimed |
| US-20130261270-A1 | POLYAMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS | SIKA TECHNOLOGY AG (CH) | 2013-10-03 | — | — | US | claimed |
| EP-2468759-A1 | Secondary Aminosilanes | Sika Technology AG (CH) | 2012-06-27 | — | — | EP | claimed |
| WO-2012080265-A1 | POLYAMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS | SIKA TECHNOLOGY AG (CH) | 2012-06-21 | — | — | WO | claimed |
| EP-2465843-A1 | Polyamines with secondary aliphatic amines | Sika Technology AG (CH) | 2012-06-20 | — | — | EP | claimed |
| EP-3484898-B1 | METHOD OF STABILIZING IMINO-FUNCTIONAL SILANE | MOMENTIVE PERFORMANCE MAT INC (US) | 2023-06-28 | — | — | EP | disclosed |
| EP-4053134-A1 | METHOD OF STABILIZING IMINO-FUNCTIONAL SILANE | Momentive Performance Materials Inc. (US) | 2022-09-07 | — | — | EP | disclosed |
| CN-109563111-B | Method for stabilizing imino-functional silanes | 莫门蒂夫性能材料股份有限公司 | 2022-04-12 | — | — | CN | disclosed |
| US-11230563-B2 | Method of stabilizing imino-functional silane | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2022-01-25 | — | — | US | disclosed |
| EP-3350157-B1 | COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS | MODERNATX INC (US) | 2022-01-05 | — | — | EP | disclosed |
| US-10457697-B2 | Method of stabilizing imino-functional silane | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2019-10-29 | — | — | US | disclosed |
| US-6136826-A | AMINOPIPERIDINE COMPOUNDS SUBSTITUTED WITH ALKANOYL | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2000-10-24 | — | — | US | disclosed |
| CN-1052224-C | Peripheral Vasodilating agent containing N-acylated 4-amino piperidine derivatives as active ingredients | OTSUKA PHARMA CO LTD (JP) | 2000-05-10 | — | — | CN | disclosed |
| US-5760058-A | Peripheral vasodilating agent containing piperidine derivative as active ingredient | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-06-02 | — | — | US | disclosed |
| US-5656642-A | Peripheral vasodilating agent containing piperidine derivative as active ingredient | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-08-12 | — | — | US | disclosed |
| EP-0650476-A1 | PERIPHERAL VASODILATING AGENT CONTAINING N-ACYLATED 4-AMINO PIPERIDINE DERIVATIVES AS ACTIVE INGREDIENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-05-03 | — | — | EP | disclosed |
| WO-1994022826-A1 | PERIPHERAL VASODILATING AGENT CONTAINING N-ACYLATED 4-AMINO PIPERIDINE DERIVATIVES AS ACTIVE INGREDIENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11230563-B2 | Method of stabilizing imino-functional silane | INF2, RNF168, BOLA2; BOLA2B | ADH1B 3143/4885ADH1A 1807/4885ADH7 2196/4885 |
| US-20130281562-A1 | SECONDARY AMINOSILANES | AS3MT, SRM, MSN | ADH1B 4383/4885ADH1A 3967/4885ADH7 4282/4885 |
| US-10457697-B2 | Method of stabilizing imino-functional silane | INF2, RNF168, BOLA2; BOLA2B | ADH1B 3143/4885ADH1A 1807/4885ADH7 2196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.