Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 9/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.38 |
| ▸ | FKBP4 | Q02790 | 1/20 | 0.38 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7469127 | 0.82 | FKBP1A (0.42) | FKBP1AKDM4EALDH1A1ALOX15ABCC1 | |
| SCHEMBL7463764 | 0.81 | FKBP1A (0.61) | FKBP1AABCC1FKBP4FKBP5 | |
| SCHEMBL7462356 | 0.77 | FKBP1A (0.51) | FKBP1AKDM4EALDH1A1ALOX15EPHX2 | |
| SCHEMBL7469826 | 0.77 | FKBP1A (0.49) | FKBP1AABCC1FKBP4FKBP5 | |
| SCHEMBL7469115 | 0.74 | FKBP1A (0.47) | FKBP1AKDM4EALDH1A1ALOX15EPHX2 | |
| SCHEMBL7561503 | 0.73 | FKBP1A (0.45) | FKBP1AFKBP4FKBP5 | |
| SCHEMBL5966088 | 0.68 | FKBP1A (0.60) | FKBP1ATBXAS1ABCC1FKBP4FKBP5 | |
| SCHEMBL28746637 | 0.66 | FKBP1A (0.66) | FKBP1ATBXAS1ABCC1FKBP4FKBP5 | |
| SCHEMBL8938447 | 0.64 | ACE (0.51) | FKBP1AKDM4EALDH1A1ALOX15TBXAS1 | |
| SCHEMBL5966068 | 0.64 | FKBP1A (1.00) | FKBP1AFKBP4FKBP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1204657-A1 | PIPERIDINE AND PYRROLIDINE DERIVATIVES DISPLAYING NEURONAL ACTIVITY | SCHERING AKTIENGESELLSCHAFT (DE) | 2002-05-15 | — | — | EP | claimed |
| WO-2001012622-A1 | PIPERIDINE AND PYRROLIDINE DERIVATIVES DISPLAYING NEURONAL ACTIVITY | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-02-22 | — | — | WO | claimed |
| EP-1204657-A1 | PIPERIDINE AND PYRROLIDINE DERIVATIVES DISPLAYING NEURONAL ACTIVITY | SCHERING AKTIENGESELLSCHAFT (DE) | 2002-05-15 | — | — | EP | disclosed |
| WO-2001012622-A1 | PIPERIDINE AND PYRROLIDINE DERIVATIVES DISPLAYING NEURONAL ACTIVITY | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-02-22 | — | — | WO | disclosed |