Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 18/20 | 0.49 |
| ▸ | FKBP4 | Q02790 | 2/20 | 0.47 |
| ▸ | FKBP5 | Q13451 | 2/20 | 0.47 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7463764 | 0.87 | FKBP1A (0.61) | FKBP1AFKBP4FKBP5ABCC1 | |
| SCHEMBL7469832 | 0.84 | FKBP1A (0.46) | FKBP1AFKBP4FKBP5ABCC1MEN1 | |
| SCHEMBL7561503 | 0.79 | FKBP1A (0.45) | FKBP1AFKBP4FKBP5 | |
| SCHEMBL7469822 | 0.77 | FKBP1A (0.49) | FKBP1AFKBP4FKBP5ABCC1MEN1 | |
| SCHEMBL7469124 | 0.77 | FKBP1A (0.47) | FKBP1AFKBP4FKBP5ABCC1 | |
| SCHEMBL7463766 | 0.72 | FKBP1A (0.57) | FKBP1AFKBP4FKBP5ABCC1 | |
| SCHEMBL7469859 | 0.69 | FKBP1A (0.53) | FKBP1AFKBP4FKBP5ABCC1 | |
| SCHEMBL7463760 | 0.68 | FKBP1A (0.62) | FKBP1AFKBP4FKBP5ABCC1 | |
| SCHEMBL16310240 | 0.66 | FKBP1A (0.89) | FKBP1AFKBP4FKBP5ABCC1 | |
| SCHEMBL7470083 | 0.66 | FKBP1A (0.57) | FKBP1AFKBP4FKBP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1204657-A1 | PIPERIDINE AND PYRROLIDINE DERIVATIVES DISPLAYING NEURONAL ACTIVITY | SCHERING AKTIENGESELLSCHAFT (DE) | 2002-05-15 | — | — | EP | claimed |
| WO-2001012622-A1 | PIPERIDINE AND PYRROLIDINE DERIVATIVES DISPLAYING NEURONAL ACTIVITY | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-02-22 | — | — | WO | claimed |