Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 4/20 | 0.51 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8938580 | 0.90 | MEN1 (0.50) | ACEKMT2AMEN1NPC1RAB9A | |
| SCHEMBL8938415 | 0.83 | MEN1 (0.49) | KMT2AMEN1NPC1RAB9AKDM4E | |
| SCHEMBL8938420 | 0.81 | MEN1 (0.47) | KMT2AMEN1NPC1RAB9AALDH1A1 | |
| SCHEMBL8938520 | 0.80 | MEN1 (0.47) | FKBP1AKMT2AMEN1NPC1RAB9A | |
| SCHEMBL8938648 | 0.80 | FAAH (0.48) | FKBP1AKMT2AMEN1NPC1RAB9A | |
| SCHEMBL8938620 | 0.80 | PLA2G4A (0.48) | KMT2AMEN1NPC1RAB9A | |
| SCHEMBL8938585 | 0.80 | PREP (0.58) | KMT2AMEN1NPC1RAB9A | |
| SCHEMBL8938499 | 0.79 | MEN1 (0.48) | KMT2AMEN1NPC1RAB9A | |
| SCHEMBL8938439 | 0.79 | MEN1 (0.50) | KMT2AMEN1NPC1RAB9A | |
| SCHEMBL8938600 | 0.79 | MEN1 (0.45) | KMT2AMEN1NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5547978-A | ENDOPEPTIDASE INHIBITORS | MEIJI SEIKA KAISHA, LTD. (JP) | 1996-08-20 | — | — | US | disclosed |