Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 4/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7470900 | 0.87 | ALDH1A1 (0.51) | ALDH1A1MAPTKMT2AKDM4EPOLB | |
| SCHEMBL7661297 | 0.82 | ALDH1A1 (0.56) | ALDH1A1MAPTKMT2AKDM4EPOLB | |
| SCHEMBL7612770 | 0.82 | ALDH1A1 (0.56) | ALDH1A1MGLL | |
| SCHEMBL8419857 | 0.76 | CA12 (0.47) | ALDH1A1MAPTCA1CA2CA12 | |
| SCHEMBL7614930 | 0.75 | ALDH1A1 (0.55) | ALDH1A1MAPTKMT2AKDM4EGLA | |
| Hydrochloric Acid SCHEMBL9793009 | 0.75 | CA12 (0.46) | ALDH1A1MAPTKMT2ACA1CA2 | |
| SCHEMBL14831731 | 0.75 | MAPT (0.47) | ALDH1A1MAPTKDM4ETSHRLMNA | |
| SCHEMBL143046 | 0.75 | ALDH1A1 (0.40) | ALDH1A1MAPTKMT2AACHESMN1; SMN2 | |
| SCHEMBL13253174 | 0.74 | ALDH1A1 (0.60) | ALDH1A1MAPTKMT2AKDM4EPOLB | |
| SCHEMBL15754569 | 0.74 | ALDH1A1 (0.53) | ALDH1A1MAPTKMT2APOLBCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711768-B1 | BENZIMIDAZOLE DERIVATIVE | MITSUI CHEMICALS INC (JP) | 2002-02-13 | — | — | EP | disclosed |
| US-5852011-A | Benzimidazole derivatives | MITSUI CHEMICALS, INC. (JP) | 1998-12-22 | — | — | US | disclosed |
| EP-0711768-A1 | BENZIMIDAZOLE DERIVATIVE | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-15 | — | — | EP | disclosed |