Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.36 |
| ▸ | HTR3B | O95264 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.36 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.36 |
| ▸ | GAK | O14976 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14846134 | 0.80 | ALDH1A1 (0.35) | ALDH1A1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL8419857 | 0.78 | CA12 (0.47) | ALDH1A1GAAMAPTKEAP1NFE2L2 | |
| Hydrochloric Acid SCHEMBL9793009 | 0.76 | CA12 (0.46) | ALDH1A1GAAMAPTKEAP1NFE2L2 | |
| SCHEMBL14831731 | 0.76 | MAPT (0.47) | ALDH1A1GAKSMN1; SMN2GAAMAPT | |
| Hydrochloric Acid SCHEMBL14833948 | 0.75 | GAA (0.46) | ALDH1A1GAKSMN1; SMN2GAAMAPT | |
| SCHEMBL7469423 | 0.75 | ALDH1A1 (0.68) | ALDH1A1SMN1; SMN2MAPTACHEMEN1 | |
| SCHEMBL18077348 | 0.75 | ALDH1A1 (0.40) | ALDH1A1GAKSMN1; SMN2GAAMAPT | |
| SCHEMBL7466490 | 0.74 | HTT (0.53) | ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL14846133 | 0.73 | ALDH1A1 (0.38) | ALDH1A1GAKSMN1; SMN2GAAMAPT | |
| SCHEMBL16026884 | 0.73 | MEN1 (0.40) | ALDH1A1GAKGAAMAPTADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11851685-B2 | Zwitterion buffer containing compositions and uses in electroanalytical devices and methods | ROCHE DIABETES CARE, INC. (US) | 2023-12-26 | — | — | US | claimed |
| US-5286362-A | Reducible substance is enzymatically reduced and oxidized at the electrode; substance formed by oxidation is different from the reducible substance used initially | BOEHRINGER MANNHEIM GMBH (DE) | 1994-02-15 | — | — | US | claimed |
| EP-4481375-A2 | DETECTION REAGENTS AND ELECTRODE ARRANGEMENTS FOR MULTI-ANALYTE DIAGNOSTIC TEST ELEMENTS, AS WELL AS METHODS OF USING THE SAME | F. Hoffmann-La Roche AG (CH) | 2024-12-25 | — | — | EP | disclosed |
| EP-3523639-B1 | DETECTION REAGENTS AND ELECTRODE ARRANGEMENTS FOR MULTI-ANALYTE DIAGNOSTIC TEST ELEMENTS, AS WELL AS METHODS OF USING THE SAME | HOFFMANN LA ROCHE (CH) | 2024-12-18 | — | — | EP | disclosed |
| US-20240327892-A1 | DETECTION REAGENTS AND ELECTRODE ARRANGEMENTS FOR MULTI-ANALYTE DIAGNOSTIC TEST ELEMENTS, AS WELL AS METHODS OF USING THE SAME | ROCHE DIABETES CARE, INC. | 2024-10-03 | — | — | US | disclosed |
| US-12024735-B2 | Detection reagents and electrode arrangements for multi-analyte diagnostic test elements, as well as methods of using the same | ROCHE DIABETES CARE, INC. (US) | 2024-07-02 | — | — | US | disclosed |
| US-11851685-B2 | Zwitterion buffer containing compositions and uses in electroanalytical devices and methods | ROCHE DIABETES CARE, INC. (US) | 2023-12-26 | — | — | US | disclosed |
| EP-4152003-A1 | SYSTEMS AND METHODS FOR MULTIPLE ANALYTE ANALYSIS | Roche Diabetes Care GmbH (DE) | 2023-03-22 | — | — | EP | disclosed |
| EP-3757574-B1 | SYSTEMS AND METHODS FOR MULTIPLE ANALYTE ANALYSIS | ROCHE DIABETES CARE GMBH (DE) | 2022-12-07 | — | — | EP | disclosed |
| US-20220275348-A1 | ZWITTERION BUFFER CONTAINING COMPOSITIONS AND USES IN ELECTROANALYTICAL DEVICES AND METHODS | ROCHE DIABETES CARE, INC. | 2022-09-01 | — | — | US | disclosed |
| US-20220098636-A1 | DETECTION REAGENTS AND ELECTRODE ARRANGEMENTS FOR MULTI-ANALYTE DIAGNOSTIC TEST ELEMENTS, AS WELL AS METHODS OF USING THE SAME | ROCHE DIABETES CARE, INC. (US) | 2022-03-31 | — | — | US | disclosed |
| US-20050016844-A1 | Reagent stripe for test strip | ROCHE DIABETES CARE, INC. | 2005-01-27 | — | — | US | disclosed |
| US-20050013731-A1 | Test strip with slot vent opening | ROCHE DIABETES CARE, INC. | 2005-01-20 | — | — | US | disclosed |
| WO-2004113902-A1 | REAGENT STRIPE FOR TEST STRIP | ROCHE DIAGNOSTICS GMBH (DE) | 2004-12-29 | — | — | WO | disclosed |
| WO-2004113901-A1 | TEST STRIP WITH SLOT VENT OPENING | ROCHE DIAGNOSTICS GMBH (DE) | 2004-12-29 | — | — | WO | disclosed |
| WO-2004113900-A2 | TEST STRIP WITH FLARED SAMPLE RECEIVING CHAMBER | ROCHE DIAGNOSTICS GMBH (DE) | 2004-12-29 | — | — | WO | disclosed |
| EP-0441222-B1 | Process and electrode system for determining an analyte or an oxidoreductase as well as suitable compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1996-12-18 | — | — | EP | disclosed |
| US-5286362-A | Reducible substance is enzymatically reduced and oxidized at the electrode; substance formed by oxidation is different from the reducible substance used initially | BOEHRINGER MANNHEIM GMBH (DE) | 1994-02-15 | — | — | US | disclosed |
| US-5122244-A | Having a reducible nitroso or oxime compound to transfer electrons leading to a signal and form an aromatic amine oxidizable to a compound different from the original; low voltage | BOEHRINGER MANNHEIM GMBH (DE) | 1992-06-16 | — | — | US | disclosed |
| EP-0441222-A2 | Process and electrode system for determining an analyte or an oxidoreductase as well as suitable compounds | Roche Diagnostics GmbH (DE) | 1991-08-14 | — | — | EP | disclosed |