Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TACR1 | P25103 | 6/20 | 0.48 |
| ▸ | NMBR | P28336 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7469433 | 0.83 | TACR1 (0.69) | TACR1 | |
| SCHEMBL7847648 | 0.81 | CCKBR (0.53) | CCKBRMEN1NPC1POLBMAPT | |
| SCHEMBL7529398 | 0.78 | TACR1 (0.61) | CCKBRMEN1NPC1POLBMAPT | |
| SCHEMBL7529387 | 0.78 | TACR1 (0.61) | CCKBRMEN1NPC1POLBMAPT | |
| Hydrochloric Acid SCHEMBL7569286 | 0.78 | TACR1 (0.60) | CCKBRMEN1NPC1POLBMAPT | |
| Hydrochloric Acid SCHEMBL7569288 | 0.78 | TACR1 (0.60) | CCKBRMEN1NPC1POLBMAPT | |
| SCHEMBL7438201 | 0.78 | TACR1 (0.73) | CCKBRTACR1 | |
| SCHEMBL7846982 | 0.77 | BRS3 (0.60) | MEN1NPC1POLBMAPTRAB9A | |
| SCHEMBL7523633 | 0.75 | TACR1 (0.68) | TACR1 | |
| SCHEMBL7061471 | 0.75 | TACR1 (0.53) | CCKBRMEN1NPC1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1244653-A1 | NON PEPTIDE TACHYKININ RECEPTOR ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 2002-10-02 | — | — | EP | disclosed |
| WO-2001046176-A2 | NON PEPTIDE TACHYKININ RECEPTOR ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 2001-06-28 | — | — | WO | disclosed |