Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRS3 | P32247 | 10/20 | 0.60 |
| ▸ | NMBR | P28336 | 5/20 | 0.56 |
| ▸ | KCNT1 | Q5JUK3 | 1/20 | 0.54 |
| ▸ | TACR1 | P25103 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7848664 | 0.83 | MC5R (0.61) | KCNT1TACR1KMT2AMEN1NPC1 | |
| SCHEMBL7062961 | 0.82 | TACR1 (0.76) | TACR1KMT2AMEN1 | |
| SCHEMBL7064065 | 0.79 | TACR1 (0.68) | TACR1MAPTSMN1; SMN2 | |
| SCHEMBL7067777 | 0.78 | TACR1 (0.67) | TACR1 | |
| SCHEMBL7062825 | 0.78 | TACR1 (0.74) | TACR1KMT2AMEN1 | |
| SCHEMBL27763689 | 0.77 | BRS3 (0.85) | BRS3NMBRKMT2A | |
| SCHEMBL7469438 | 0.77 | CCKBR (0.49) | NMBRTACR1KMT2AMEN1NPC1 | |
| SCHEMBL1274233 | 0.76 | BRS3 (0.74) | BRS3NMBRKMT2A | |
| SCHEMBL7253751 | 0.76 | BRS3 (0.72) | BRS3NMBRKMT2A | |
| SCHEMBL1273642 | 0.76 | BRS3 (0.72) | BRS3NMBRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140914-A1 | NON-PEPTIDE NK1 RECEPTORS ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000037462-A1 | NON-PEPTIDE NK1 RECEPTORS ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 2000-06-29 | — | — | WO | disclosed |