Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 10/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7462193 | 0.98 | PTPN1 (0.41) | PTPN1MAPK1KDM4EALDH1A1TP53 | |
| SCHEMBL6939678 | 0.93 | GPR84 (0.46) | PTPN1MAPK1KDM4EALDH1A1TP53 | |
| SCHEMBL7462188 | 0.84 | PTPN1 (0.34) | PTPN1MAPK1ALDH1A1TP53POLB | |
| SCHEMBL8890653 | 0.81 | ALDH1A1 (0.47) | MAPK1KDM4EALDH1A1TP53GLA | |
| SCHEMBL6937699 | 0.81 | ALDH1A1 (0.40) | MAPK1KDM4EALDH1A1TP53GLA | |
| SCHEMBL133528 | 0.80 | POLB (0.68) | MAPK1KDM4EALDH1A1TP53GLA | |
| SCHEMBL29783279 | 0.80 | POLB (0.68) | MAPK1KDM4EALDH1A1TP53GLA | |
| Hydrochloric Acid SCHEMBL7473828 | 0.79 | ALDH1A1 (0.39) | MAPK1KDM4EALDH1A1TP53GLA | |
| Hydrochloric Acid SCHEMBL7757351 | 0.79 | POLB (0.66) | MAPK1KDM4EALDH1A1TP53GLA | |
| SCHEMBL6941606 | 0.79 | PTPN1 (0.41) | PTPN1MAPK1KDM4EALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0813546-B1 | PHOTOCHEMICALLY CROSS-LINKED POLYSACCHARIDE DERIVATIVES AS SUPPORTS FOR THE CHROMATOGRAPHIC SEPARATION OF ENANTIOMERS | NOVARTIS AG (CH) | 2002-07-17 | — | — | EP | disclosed |
| US-6011149-A | ESTERIFICATION; CARBAMYLATION | NOVARTIS AG (CH) | 2000-01-04 | — | — | US | disclosed |
| EP-0813546-A1 | PHOTOCHEMICALLY CROSS-LINKED POLYSACCHARIDE DERIVATIVES AS SUPPORTS FOR THE CHROMATOGRAPHIC SEPARATION OF ENANTIOMERS | Novartis AG (CH) | 1997-12-29 | — | — | EP | disclosed |
| WO-1996027615-A1 | PHOTOCHEMICALLY CROSS-LINKED POLYSACCHARIDE DERIVATIVES AS SUPPORTS FOR THE CHROMATOGRAPHIC SEPARATION OF ENANTIOMERS | NOVARTIS AG (CH) | 1996-09-12 | — | — | WO | disclosed |