Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 4/20 | 0.60 |
| ▸ | HTT | P42858 | 6/20 | 0.53 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.49 |
| ▸ | PDE5A | O76074 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | FBP1 | P09467 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7469664 | 0.92 | HTT (0.63) | EGFRHTTNR2F2PDE5AMAPK1 | |
| SCHEMBL7474665 | 0.90 | HTT (0.62) | EGFRHTTNR2F2PDE5AMAPK1 | |
| SCHEMBL7475626 | 0.90 | HTT (0.52) | EGFRHTTNR2F2PDE5AMAPK1 | |
| SCHEMBL7464363 | 0.90 | HTT (0.54) | EGFRHTTNR2F2PDE5AMAPK1 | |
| SCHEMBL7474181 | 0.90 | MAPK1 (0.56) | EGFRHTTNR2F2MAPK1SMN1; SMN2 | |
| SCHEMBL7528662 | 0.89 | EGFR (0.52) | EGFRHTTNR2F2PDE5AMAPK1 | |
| SCHEMBL7465161 | 0.88 | PDE5A (0.52) | EGFRHTTPDE5AMAPK1MEN1 | |
| SCHEMBL7462734 | 0.85 | EGFR (0.55) | EGFRHTTNR2F2MAPK1MEN1 | |
| SCHEMBL7463417 | 0.84 | EGFR (0.49) | EGFRHTTNR2F2NTRK1CNR1 | |
| SCHEMBL7471567 | 0.84 | PIK3CD (0.62) | EGFRHTTMAPK1CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |