Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 4/20 | 0.37 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7472397 | 0.86 | GRIN1 (0.35) | ALDH1A1SMN1; SMN2MAPTLMNAGRIN1 | |
| SCHEMBL8645693 | 0.84 | KMT2A (0.32) | ALDH1A1SMN1; SMN2PDCD1LG2CD274PKM | |
| SCHEMBL8930335 | 0.79 | GRIN1 (0.38) | CD274GRIN1 | |
| SCHEMBL8650855 | 0.78 | GRIN1 (0.42) | PKMGRIN1KMT2A | |
| SCHEMBL7470542 | 0.76 | GRIN1 (0.39) | PKMGRIN1KMT2A | |
| SCHEMBL8488510 | 0.75 | GRIN1 (0.49) | ALDH1A1SMN1; SMN2KDM4EMAPTPKM | |
| SCHEMBL7467566 | 0.75 | GRIN1 (0.39) | ALDH1A1SMN1; SMN2KDM4EMAPTPKM | |
| SCHEMBL8649190 | 0.75 | GRIN1 (0.34) | ALDH1A1PDCD1LG2CD274MAPTPKM | |
| SCHEMBL7476576 | 0.74 | GRIN1 (0.35) | GRIN1 | |
| SCHEMBL8489890 | 0.74 | GRIN1 (0.37) | ALDH1A1KDM4EMAPTPKMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0783495-B1 | QUINOXALINE DERIVATIVES USEFUL IN THERAPY | PFIZER LTD (GB) | 2002-02-27 | — | — | EP | disclosed |
| US-5852016-A | Quinoxaline derivatives useful in therapy | PFIZER INC. (US) | 1998-12-22 | — | — | US | disclosed |