Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | PDCD1LG2 | Q9BQ51 | 3/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.30 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8649190 | 0.85 | GRIN1 (0.34) | KMT2AMEN1PKMPDCD1LG2CD274 | |
| SCHEMBL7469799 | 0.84 | RAD52 (0.37) | KMT2APKMPDCD1LG2CD274ALDH1A1 | |
| SCHEMBL7471934 | 0.76 | GRIN1 (0.50) | KMT2AMEN1PKMALDH1A1GRIN1 | |
| SCHEMBL7470510 | 0.74 | RAB9A (0.46) | KMT2AMEN1PKMALDH1A1LMNA | |
| SCHEMBL8489890 | 0.74 | GRIN1 (0.37) | KMT2AMEN1PKMALDH1A1LMNA | |
| SCHEMBL7472397 | 0.73 | GRIN1 (0.35) | KMT2AALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL8488510 | 0.73 | GRIN1 (0.49) | KMT2AMEN1PKMALDH1A1SMN1; SMN2 | |
| SCHEMBL7467566 | 0.73 | GRIN1 (0.39) | KMT2AMEN1PKMALDH1A1LMNA | |
| SCHEMBL8649192 | 0.73 | PDCD1LG2 (0.41) | PDCD1LG2CD274ALDH1A1 | |
| SCHEMBL8650855 | 0.72 | GRIN1 (0.42) | KMT2AMEN1PKMGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852016-A | Quinoxaline derivatives useful in therapy | PFIZER INC. (US) | 1998-12-22 | — | — | US | disclosed |