Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 15/20 | 0.53 |
| ▸ | FKBP4 | Q02790 | 2/20 | 0.49 |
| ▸ | FKBP5 | Q13451 | 2/20 | 0.49 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7469822 | 0.80 | FKBP1A (0.49) | FKBP1AFKBP4FKBP5ABCC1 | |
| SCHEMBL7470214 | 0.79 | FKBP1A (0.58) | FKBP1AFKBP4FKBP5ABCC1ALDH1A1 | |
| SCHEMBL7469652 | 0.75 | FKBP1A (0.67) | FKBP1AFKBP4FKBP5ABCC1 | |
| SCHEMBL7463760 | 0.74 | FKBP1A (0.62) | FKBP1AFKBP4FKBP5ABCC1 | |
| SCHEMBL7469832 | 0.71 | FKBP1A (0.46) | FKBP1AFKBP4FKBP5ABCC1 | |
| SCHEMBL6573934 | 0.69 | L3MBTL1 (0.40) | FKBP1AALDH1A1 | |
| SCHEMBL6573929 | 0.69 | L3MBTL1 (0.40) | FKBP1AALDH1A1 | |
| SCHEMBL7469826 | 0.69 | FKBP1A (0.49) | FKBP1AFKBP4FKBP5ABCC1 | |
| SCHEMBL18574236 | 0.69 | FKBP1A (0.79) | FKBP1AFKBP4FKBP5ABCC1 | |
| SCHEMBL12579115 | 0.69 | FKBP1A (0.79) | FKBP1AFKBP4FKBP5ABCC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1204657-A1 | PIPERIDINE AND PYRROLIDINE DERIVATIVES DISPLAYING NEURONAL ACTIVITY | SCHERING AKTIENGESELLSCHAFT (DE) | 2002-05-15 | — | — | EP | disclosed |
| WO-2001012622-A1 | PIPERIDINE AND PYRROLIDINE DERIVATIVES DISPLAYING NEURONAL ACTIVITY | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-02-22 | — | — | WO | disclosed |