Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 3/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | LSS | P48449 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7475141 | 0.88 | GAA (0.48) | MEN1KMT2AKDM4EL3MBTL1TP53 | |
| SCHEMBL7465164 | 0.87 | SMN1; SMN2 (0.55) | TSHRKDM4EL3MBTL1GAAPKM | |
| Tert-Butyl Formate SCHEMBL28108074 | 0.73 | MAPT (0.58) | TSHRMEN1KMT2AKDM4EL3MBTL1 | |
| SCHEMBL7135994 | 0.72 | PKM (0.58) | MEN1KMT2AKDM4EL3MBTL1GAA | |
| SCHEMBL266490 | 0.72 | MEN1 (0.75) | MEN1KMT2AKDM4EL3MBTL1PKM | |
| SCHEMBL7469891 | 0.70 | HTR2A (0.48) | TSHRMEN1KMT2AL3MBTL1TP53 | |
| SCHEMBL1711115 | 0.69 | PKM (0.85) | TSHRMEN1KMT2AKDM4EL3MBTL1 | |
| SCHEMBL2060140 | 0.69 | KMT2A (0.61) | MEN1KMT2AL3MBTL1GAAPKM | |
| SCHEMBL2060095 | 0.69 | PKM (0.62) | MEN1KMT2AKDM4EL3MBTL1GAA | |
| SCHEMBL7132664 | 0.68 | PKM (0.53) | TSHRMEN1KMT2AKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |