Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | PKLR | P30613 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | CCR6 | P51684 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7469895 | 0.87 | TSHR (0.53) | ALDH1A1CYP2D6PKMHTTKDM4E | |
| SCHEMBL7475141 | 0.87 | GAA (0.48) | SMN1; SMN2ALDH1A1PKMNPC1KDM4E | |
| SCHEMBL23178943 | 0.74 | PKM (0.75) | SMN1; SMN2MAPTALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL1722721 | 0.73 | PKM (1.00) | SMN1; SMN2MAPTALDH1A1PKMNPC1 | |
| SCHEMBL31315853 | 0.73 | PKM (1.00) | SMN1; SMN2MAPTALDH1A1PKMNPC1 | |
| SCHEMBL7471529 | 0.73 | PKM (0.73) | SMN1; SMN2MAPTALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL17007474 | 0.72 | ALDH1A1 (0.97) | SMN1; SMN2MAPTALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL7465150 | 0.70 | PKM (0.56) | SMN1; SMN2MAPTALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL1044915 | 0.70 | HTT (0.96) | SMN1; SMN2MAPTALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL8207637 | 0.70 | SMN1; SMN2 (0.59) | SMN1; SMN2MAPTALDH1A1CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |