Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CCR6 | P51684 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7469895 | 0.88 | TSHR (0.53) | GAAKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL7465164 | 0.87 | SMN1; SMN2 (0.55) | GAAKDM4EALDH1A1L3MBTL1PKM | |
| SCHEMBL7468310 | 0.76 | ACHE (0.49) | — | |
| SCHEMBL7474256 | 0.72 | ALDH1A1 (0.54) | GAAKDM4EALDH1A1TP53NPC1 | |
| SCHEMBL17069876 | 0.72 | POLB (0.57) | GAAKDM4EMEN1KMT2APOLB | |
| SCHEMBL13152700 | 0.71 | ALDH1A1 (0.60) | GAAKDM4EMEN1KMT2APOLB | |
| SCHEMBL28471923 | 0.70 | GAA (0.58) | GAAKDM4EMEN1KMT2APOLB | |
| SCHEMBL762416 | 0.70 | KMT2A (0.74) | GAAKDM4EMEN1KMT2APOLB | |
| SCHEMBL28003015 | 0.69 | KMT2A (0.55) | GAAMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL7475133 | 0.68 | ALDH1A1 (0.50) | GAAKDM4EMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |