SCHEMBL7474149

SCHEMBL7474149

CCCOC(=O)c1scc(Cl)c1OS(=O)(=O)Cl

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
STS P08842 2/20 0.38
ALDH1A1 P00352 4/20 0.37
LMNA P02545 2/20 0.37
HPGD P15428 1/20 0.37
COMT P21964 1/20 0.37
ESR1 P03372 2/20 0.35
CHRM1 P11229 1/20 0.35
TSHR P16473 1/20 0.35
SLC6A2 P23975 1/20 0.35
KDR P35968 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
MAPT P10636 3/20 0.35
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA9 Q16790 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
TP53 P04637 1/20 0.33
KDM4E B2RXH2 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7469012 0.89 MAPT (0.41) ALDH1A1LMNAMAPTCA12CA1
SCHEMBL7466963 0.86 STS (0.38) STSALDH1A1LMNAHPGDCOMT
SCHEMBL7465252 0.86 STS (0.38) STSALDH1A1LMNAHPGDCOMT
SCHEMBL7469073 0.86 STS (0.38) STSALDH1A1LMNAHPGDCOMT
SCHEMBL7469898 0.85 STS (0.37) STSALDH1A1LMNAHPGDCOMT
SCHEMBL7471765 0.84 POLB (0.39) STSALDH1A1LMNAHPGDESR1
SCHEMBL7471848 0.83 STS (0.36) STSALDH1A1LMNAHPGDCOMT
SCHEMBL7464814 0.82 STS (0.35) STSALDH1A1LMNAHPGDCOMT
SCHEMBL7469821 0.81 KDM4E (0.42) LMNAHPGDTSHRMAPTTP53
SCHEMBL7024185 0.81 ALDH1A1 (0.38) STSALDH1A1LMNAHPGDCOMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0859774-B1 SUBSTITUTED SULPHONYLAMINO (THIO)CARBONYL COMPOUNDS AS HERBICIDES BAYER AG (DE) 2002-04-03 EP disclosed
EP-0859774-A1 SUBSTITUTED SULPHONYLAMINO (THIO)CARBONYL COMPOUNDS AS HERBICIDES BAYER AG (DE) 1998-08-26 EP disclosed
WO-1997016449-A1 SUBSTITUTED SULPHONYLAMINO (THIO)CARBONYL COMPOUNDS AS HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1997-05-09 WO disclosed