Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.51 |
| ▸ | ESR1 | P03372 | 8/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.49 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.46 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7209701 | 0.85 | ESR1 (0.62) | LTA4HESR1ESR2 | |
| SCHEMBL7778587 | 0.85 | ESR1 (0.63) | ESR1HRH3KCNH2ESR2 | |
| SCHEMBL7749392 | 0.83 | LTA4H (0.61) | LTA4HESR1HRH3KCNH2MCHR1 | |
| SCHEMBL7458270 | 0.78 | ESR1 (0.68) | ESR1HRH3ESR2 | |
| Hydrochloric Acid SCHEMBL5486653 | 0.77 | ESR1 (0.76) | ESR1ESR2 | |
| SCHEMBL7930070 | 0.77 | ESR1 (0.51) | LTA4HESR1ESR2 | |
| SCHEMBL7443460 | 0.76 | LTA4H (0.77) | LTA4HESR1HRH3KCNH2PSMB1 | |
| SCHEMBL14970684 | 0.76 | LTA4H (0.82) | LTA4HHRH3PSMB1PSMB5POLB | |
| SCHEMBL15257179 | 0.76 | LTA4H (0.82) | LTA4HHRH3PSMB1PSMB5POLB | |
| Hydrochloric Acid SCHEMBL14966283 | 0.75 | LTA4H (0.79) | LTA4HHRH3PSMB1PSMB5POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1204655-A2 | A CRYSTALLINE FORM OF 6-HYDROXY-3-(4-[2-(PIPERIDIN-1-YL)ETHOXY] PHENOXY)-2-(4-METHOXYPHENYL)BENZO[B]THIOPHENE HYDROCHLORIDE | ELI LILLY AND COMPANY (US) | 2002-05-15 | — | — | EP | disclosed |
| WO-2001009115-A2 | A NOVEL CRYSTALLINE FORM OF 6-HYDROXY-3- (4-[2-(PIPERIDIN-1- YL)ETHOXY] PHENOXY)-2- (4-METHOXYPHENYL) BENZO[b]THIOPHENE HYDROCHLORIDE | ELI LILLY AND COMPANY (US) | 2001-02-08 | — | — | WO | disclosed |