Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 19/20 | 0.63 |
| ▸ | ESR2 | Q92731 | 18/20 | 0.63 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7209701 | 0.94 | ESR1 (0.62) | ESR1ESR2 | |
| SCHEMBL7458270 | 0.91 | ESR1 (0.68) | ESR1ESR2HRH3 | |
| SCHEMBL7469979 | 0.85 | LTA4H (0.51) | ESR1ESR2KCNH2HRH3 | |
| SCHEMBL7749392 | 0.85 | LTA4H (0.61) | ESR1KCNH2HRH3 | |
| SCHEMBL7452788 | 0.82 | ESR1 (0.52) | ESR1ESR2KCNH2HRH3 | |
| SCHEMBL699174 | 0.78 | ESR1 (0.76) | ESR1ESR2HRH3 | |
| SCHEMBL1359959 | 0.78 | ESR1 (0.76) | ESR1ESR2HRH3 | |
| SCHEMBL7450925 | 0.77 | ESR1 (0.89) | ESR1ESR2KCNH2 | |
| SCHEMBL2475993 | 0.77 | ESR1 (0.75) | ESR1ESR2HRH3 | |
| SCHEMBL18951282 | 0.76 | ESR1 (0.70) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1121125-A1 | PHARMACEUTICAL FORMULATIONS FOR USE IN ESTROGEN DEPRIVATION SYNDROME | ELI LILLY AND COMPANY (US) | 2001-08-08 | — | — | EP | claimed |
| WO-2000021535-A1 | PHARMACEUTICAL FORMULATIONS FOR USE IN ESTROGEN DEPRIVATION SYNDROME | ELI LILLY AND COMPANY (US) | 2000-04-20 | — | — | WO | claimed |