Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.59 |
| ▸ | GFER | P55789 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.47 |
| ▸ | EGFR | P00533 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7459969 | 0.98 | ALDH1A1 (0.62) | ALDH1A1KMT2AGFERCYP1A2CYP2D6 | |
| SCHEMBL7465394 | 0.86 | ALDH1A1 (0.64) | ALDH1A1KMT2ALMNAABCB1EGFR | |
| SCHEMBL12123634 | 0.79 | ALDH1A1 (0.62) | ALDH1A1KMT2AGFERCYP1A2CYP2D6 | |
| SCHEMBL12123638 | 0.79 | ALDH1A1 (0.70) | ALDH1A1KMT2AGFERCYP1A2CYP2D6 | |
| SCHEMBL11826609 | 0.78 | SIGMAR1 (0.47) | — | |
| SCHEMBL27985765 | 0.77 | ALDH1A1 (0.62) | ALDH1A1KMT2ACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL10851708 | 0.77 | ALDH1A1 (0.61) | ALDH1A1KMT2AGFERCYP1A2CYP2D6 | |
| SCHEMBL10508145 | 0.77 | HPGD (0.67) | ALDH1A1KMT2ACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL7381962 | 0.77 | DRD2 (0.45) | ABCB1 | |
| SCHEMBL10507206 | 0.76 | ALDH1A1 (0.96) | ALDH1A1KMT2AGFEREGFRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0802915-B1 | CAMPTOTHECIN DERIVATIVES AND ITS MANUFACTURING METHOD | CHONG KUN DANG CORP (KR) | 2002-12-04 | — | — | EP | disclosed |
| US-6265413-B1 | WATER SOLUBILITY; ANTICARCINOGENIC AGENTS | CHONG KUN DANG CORP. (KR) | 2001-07-24 | — | — | US | disclosed |
| US-6177568-B1 | ANTINEOPLASTIC AGENTS | CHONG KUN DANG CORP. (KR) | 2001-01-23 | — | — | US | disclosed |
| WO-1996021666-A1 | CAMPTOTHECIN DERIVATIVES AND ITS MANUFACTURING METHOD | CHONG KUN DANG CORPORATION (KR) | 1996-07-18 | — | — | WO | disclosed |