SCHEMBL7470076

SCHEMBL7470076

CCc1csc(C(=O)OC(C)C)c1OS(=O)(=O)Cl

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK8 P45983 1/20 0.33
MAPK9 P45984 1/20 0.33
MAPK10 P53779 1/20 0.33
ALDH1A1 P00352 6/20 0.33
HPGD P15428 4/20 0.33
LMNA P02545 2/20 0.33
KDM4E B2RXH2 4/20 0.32
MAPK1 P28482 2/20 0.32
GAA P10253 2/20 0.32
POLB P06746 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
CA12 O43570 4/20 0.32
CA1 P00915 4/20 0.32
CA2 P00918 4/20 0.32
CA9 Q16790 4/20 0.32
COMT P21964 1/20 0.32
KMT2A Q03164 1/20 0.32
CA7 P43166 3/20 0.31
CA14 Q9ULX7 3/20 0.31
MAPT P10636 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7464794 0.86 KDM4E (0.44) MAPK8MAPK9MAPK10LMNAKDM4E
SCHEMBL7471026 0.84 COMT (0.34) MAPK8MAPK9MAPK10ALDH1A1HPGD
SCHEMBL7468005 0.84 ALDH1A1 (0.36) MAPK8MAPK9MAPK10ALDH1A1HPGD
SCHEMBL7470040 0.84 ALDH1A1 (0.41) ALDH1A1LMNAMAPK1GAAPOLB
SCHEMBL8559545 0.84 CA12 (0.34) MAPK8MAPK9MAPK10ALDH1A1HPGD
SCHEMBL7478305 0.83 COMT (0.34) MAPK8MAPK9MAPK10ALDH1A1HPGD
SCHEMBL7471165 0.82 PRKCI (0.37) MAPK8MAPK9MAPK10ALDH1A1HPGD
SCHEMBL7466963 0.82 STS (0.38) ALDH1A1HPGDLMNAKDM4EMAPK1
SCHEMBL7023383 0.82 MAPK8 (0.34) MAPK8MAPK9MAPK10ALDH1A1HPGD
SCHEMBL7473950 0.81 LMNA (0.32) MAPK8MAPK9MAPK10ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0859774-B1 SUBSTITUTED SULPHONYLAMINO (THIO)CARBONYL COMPOUNDS AS HERBICIDES BAYER AG (DE) 2002-04-03 EP disclosed
EP-0859774-A1 SUBSTITUTED SULPHONYLAMINO (THIO)CARBONYL COMPOUNDS AS HERBICIDES BAYER AG (DE) 1998-08-26 EP disclosed
WO-1997016449-A1 SUBSTITUTED SULPHONYLAMINO (THIO)CARBONYL COMPOUNDS AS HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1997-05-09 WO disclosed