SCHEMBL7470040

SCHEMBL7470040

CCOC(=O)c1scc(CC)c1OS(=O)(=O)Cl

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.41
POLB P06746 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
MAPK1 P28482 1/20 0.41
MAPT P10636 6/20 0.38
LMNA P02545 3/20 0.38
THRB P10828 1/20 0.38
GAA P10253 2/20 0.38
NPSR1 Q6W5P4 1/20 0.38
KMT2A Q03164 3/20 0.38
MEN1 O00255 2/20 0.38
ATM Q13315 1/20 0.38
CYP2C9 P11712 2/20 0.37
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
TSHR P16473 1/20 0.37
CYP2C19 P33261 1/20 0.37
HSD17B10 Q99714 1/20 0.37
TP53 P04637 3/20 0.36
GSK3B P49841 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7466963 0.89 STS (0.38) ALDH1A1POLBSMN1; SMN2MAPK1MAPT
SCHEMBL7464794 0.87 KDM4E (0.44) MAPTLMNATHRBGAAKMT2A
SCHEMBL7466240 0.87 MAPT (0.39) ALDH1A1POLBSMN1; SMN2MAPTLMNA
SCHEMBL7472780 0.86 MAPT (0.39) ALDH1A1POLBSMN1; SMN2MAPTLMNA
SCHEMBL7469012 0.86 MAPT (0.41) ALDH1A1POLBMAPK1MAPTLMNA
SCHEMBL7470076 0.84 MAPK8 (0.33) ALDH1A1POLBSMN1; SMN2MAPK1MAPT
SCHEMBL7470407 0.84 MAPT (0.45) ALDH1A1SMN1; SMN2MAPK1MAPTLMNA
SCHEMBL7463597 0.83 MAPT (0.44) ALDH1A1POLBSMN1; SMN2MAPTLMNA
SCHEMBL7477592 0.82 LMNA (0.37) ALDH1A1POLBSMN1; SMN2MAPK1MAPT
SCHEMBL8556270 0.82 MAPT (0.37) ALDH1A1POLBSMN1; SMN2MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0859774-B1 SUBSTITUTED SULPHONYLAMINO (THIO)CARBONYL COMPOUNDS AS HERBICIDES BAYER AG (DE) 2002-04-03 EP disclosed
EP-0859774-A1 SUBSTITUTED SULPHONYLAMINO (THIO)CARBONYL COMPOUNDS AS HERBICIDES BAYER AG (DE) 1998-08-26 EP disclosed