Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.41 |
| ▸ | TGM2 | P21980 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28975265 | 0.98 | ALDH1A1 (0.46) | ALDH1A1TLR9GAANPSR1F2 | |
| SCHEMBL27915362 | 0.84 | ALDH5A1 (0.42) | GAATGM2MEN1KMT2ALMNA | |
| SCHEMBL10408130 | 0.81 | THRB (0.42) | ALDH1A1TLR9NPSR1TGM2KMT2A | |
| SCHEMBL5051695 | 0.81 | ALDH1A1 (0.46) | ALDH1A1TLR9GAANPSR1F2 | |
| SCHEMBL28013354 | 0.79 | STAT3 (0.43) | ALDH1A1TLR9GAANPSR1TGM2 | |
| SCHEMBL10637725 | 0.79 | ALDH1A1 (0.60) | ALDH1A1TLR9GAAF2PRSS1 | |
| SCHEMBL27901984 | 0.78 | CA12 (0.46) | ALDH1A1GAANPSR1F2PRSS1 | |
| SCHEMBL4594786 | 0.78 | THRB (0.44) | ALDH1A1GAANPSR1KMT2ACA1 | |
| SCHEMBL9350900 | 0.78 | NPSR1 (0.40) | ALDH1A1TLR9GAANPSR1TGM2 | |
| SCHEMBL443434 | 0.77 | ALDH1A1 (0.53) | ALDH1A1TLR9GAAF2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9718770-B2 | Substituted thioureas as heat shock protein 70 inhibitors | INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY ACADEMY OF MILITARY MEDICAL SCIENCES P.L.A. CHINA (CN) | 2017-08-01 | — | — | US | disclosed |
| CN-105713115-A | Dental Material Including Propylbarbituric Acid Polymerization Catalyst | 株式会社松风 | 2016-06-29 | — | — | CN | disclosed |
| CN-105310890-A | Dental composite material having stable pasty property | SHOFU INC | 2016-02-10 | — | — | CN | disclosed |
| CN-105310891-A | Composite material having reduced degradation of pasty property | SHOFU INC | 2016-02-10 | — | — | CN | disclosed |
| CN-104789045-A | Colored resin particle dispersion and inkjet ink | RISO KAGAKU CORP | 2015-07-22 | — | — | CN | disclosed |
| CN-104789046-A | Colored resin particle dispersion and inkjet ink | RISO KAGAKU CORP | 2015-07-22 | — | — | CN | disclosed |
| CN-104619805-A | Antistatic release agent and antistatic release film | SHINETSU POLYMER CO | 2015-05-13 | — | — | CN | disclosed |
| CN-104603226-A | Antistatic release agent and antistatic release film | SHINETSU POLYMER CO | 2015-05-06 | — | — | CN | disclosed |
| CN-103694886-A | Antistatic release agent, antistatic release coated film and antistatic release base material | SHINETSU POLYMER CO | 2014-04-02 | — | — | CN | disclosed |
| CN-102895125-A | Dental composition suitable for grinding with automatic grinding apparatus | SHOFU KK | 2013-01-30 | — | — | CN | disclosed |
| US-5622961-A | PROSTATE CANCER, SKIN DISORDERS, BALDNESS | ELI LILLY AND COMPANY (US) | 1997-04-22 | — | — | US | disclosed |
| US-5622962-A | PROSTATE CANCER, SKIN DISORDERS, BALDNESS | ELI LILLY AND COMPANY (US) | 1997-04-22 | — | — | US | disclosed |
| US-5578724-A | INHIBITORS OF 5-ALPHA-REDUCTASE | ELI LILLY AND COMPANY (US) | 1996-11-26 | — | — | US | disclosed |
| WO-1996035422-A1 | METHODS FOR INHIBITING BONE LOSS | ELI LILLY AND COMPANY (US) | 1996-11-14 | — | — | WO | disclosed |
| EP-0742010-A2 | Benzoquinolin-3-ones to inhibit bone loss | ELI LILLY AND COMPANY (US) | 1996-11-13 | — | — | EP | disclosed |
| EP-0733365-A2 | Use of benzoquinolin-3-ones for the treatment and prevention of prostatic cancer | ELI LILLY AND COMPANY (US) | 1996-09-25 | — | — | EP | disclosed |
| US-5550134-A | ADMINISTERING TO A MAMMAL FROM A SERIES OF BENZOQUINOLIN-3-ONE COMPOUNDS | ELI LILLY AND COMPANY (US) | 1996-08-27 | — | — | US | disclosed |
| WO-1996009046-A1 | 5α-REDUCTASE INHIBITORS | ELI LILLY AND COMPANY (US) | 1996-03-28 | — | — | WO | disclosed |
| EP-0703221-A1 | 5 alpha-reductase Inhibitors | ELI LILLY AND COMPANY (US) | 1996-03-27 | — | — | EP | disclosed |
| US-4806380-A | HYDROPHOBIC FIBERS IMPREGNATED WITH 2-CYANOACRYLATE | TOAGOSEI CHEMICAL INDUSTRY, CO. (JP) | 1989-02-21 | — | — | US | disclosed |