Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | KDM4D | Q6B0I6 | 7/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | BCL2 | P10415 | 1/20 | 0.45 |
| ▸ | BECN1 | Q14457 | 1/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7465144 | 0.80 | KMT2A (0.48) | HPGDALDH1A1KMT2A | |
| SCHEMBL7465181 | 0.75 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2BCL2 | |
| SCHEMBL8484888 | 0.72 | BTK (0.49) | HPGDNFKB1NFKB2RELASMN1; SMN2 | |
| SCHEMBL6331720 | 0.72 | ALDH1A1 (0.63) | HPGDALDH1A1NPC1RAB9ACYP1A2 | |
| SCHEMBL8288524 | 0.71 | ALDH1A1 (0.67) | HPGDALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL13849470 | 0.71 | MCHR1 (0.70) | — | |
| SCHEMBL16135862 | 0.70 | EPHX2 (0.54) | ALDH1A1KDM4DKMT2APOLB | |
| SCHEMBL9308869 | 0.69 | ALDH1A1 (0.58) | HPGDALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9078128 | 0.69 | HSD17B10 (0.48) | HPGDALDH1A1NPC1NFKB1NFKB2 | |
| SCHEMBL3746198 | 0.69 | BCL2 (0.45) | HPGDALDH1A1NPC1RAB9ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |