Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | BCL2 | P10415 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.43 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | PREP | P48147 | 1/20 | 0.41 |
| ▸ | FAP | Q12884 | 1/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7465144 | 0.87 | KMT2A (0.48) | ALDH1A1GAAL3MBTL1EPHX2 | |
| Hydrochloric Acid SCHEMBL5708690 | 0.81 | ALDH1A1 (0.55) | ALDH1A1HTTSMN1; SMN2LMNADPP4 | |
| SCHEMBL14731460 | 0.80 | ADORA2A (0.55) | CCNA2CDK2GAAEPHX2GPR119 | |
| SCHEMBL3208739 | 0.76 | ALDH1A1 (0.60) | ALDH1A1HTTSMN1; SMN2L3MBTL1EPHX2 | |
| SCHEMBL3208745 | 0.76 | ALDH1A1 (0.60) | ALDH1A1HTTSMN1; SMN2L3MBTL1EPHX2 | |
| SCHEMBL3766615 | 0.75 | DRD2 (0.39) | L3MBTL1EPHX2 | |
| SCHEMBL7470151 | 0.75 | HPGD (0.49) | ALDH1A1BCL2SMN1; SMN2 | |
| SCHEMBL4834357 | 0.75 | UCHL1 (0.49) | ALDH1A1KDM4ECCNA2CDK2LMNA | |
| SCHEMBL18228155 | 0.74 | HTT (0.49) | ALDH1A1BCL2HTTCCNA2CDK2 | |
| SCHEMBL27978282 | 0.74 | FKBP1A (0.52) | KDM4ELMNAPREPL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |