SCHEMBL7470469

SCHEMBL7470469

CC(N)(C(=O)O)C(=O)CCC=O

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.34
GGT1 P19440 1/20 0.31
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
CYP1A2 P05177 1/20 0.31
THRB P10828 1/20 0.31
KMT2A Q03164 1/20 0.31
ACLY P53396 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7514962 0.77 CAMK2A (0.42) GGT1MEN1ALDH1A1CYP1A2THRB
SCHEMBL3628936 0.75 HPGD (0.35) HPGDALDH1A1KMT2A
SCHEMBL3803860 0.72 FAAH (0.43) MEN1ALDH1A1CYP1A2KMT2A
SCHEMBL9422149 0.71 HPGD (0.33) HPGDALDH1A1
SCHEMBL5473167 0.71 FAAH (0.52) MEN1ALDH1A1CYP1A2KMT2A
SCHEMBL16568656 0.70 FFAR3 (0.38) GGT1MEN1ALDH1A1CYP1A2THRB
SCHEMBL4264586 0.70 GLRA1 (0.38) GGT1MEN1ALDH1A1CYP1A2THRB
SCHEMBL8108035 0.70 FAAH (0.61) MEN1CYP1A2KMT2A
SCHEMBL28095353 0.70 GGT1 (0.52) HPGDGGT1MEN1ALDH1A1CYP1A2
SCHEMBL27606031 0.69 FAAH (0.53) MEN1ALDH1A1CYP1A2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1993007867-A1 SUBSTITUTED β-AMINO ACID DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS G.D. SEARLE & CO. (US) 1993-04-29 WO disclosed