Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEP1B | Q16820 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7468148 | 0.85 | HDAC8 (0.42) | MEP1BALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL5636987 | 0.85 | MEP1B (0.57) | MEP1BALDH1A1TSHRTP53ALDH2 | |
| SCHEMBL1636569 | 0.83 | HRH3 (0.60) | MEP1BALDH1A1ALDH2MEN1KMT2A | |
| SCHEMBL4743378 | 0.80 | MEP1B (0.61) | MEP1BALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL11809995 | 0.80 | MEP1B (0.61) | MEP1BALDH1A1TSHRMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL29407386 | 0.79 | MEP1B (0.56) | MEP1BALDH1A1TSHRTP53ALDH2 | |
| SCHEMBL7471752 | 0.79 | SMN1; SMN2 (0.56) | ALDH1A1TSHRMEN1KMT2AKDM4E | |
| SCHEMBL4744604 | 0.79 | MEP1B (0.51) | MEP1BALDH1A1ALDH2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL16699939 | 0.78 | MEP1B (0.59) | MEP1BALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL4289838 | 0.78 | HDAC8 (0.66) | MEP1BALDH1A1TSHRTP53ALDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711768-B1 | BENZIMIDAZOLE DERIVATIVE | MITSUI CHEMICALS INC (JP) | 2002-02-13 | — | — | EP | disclosed |
| US-5852011-A | Benzimidazole derivatives | MITSUI CHEMICALS, INC. (JP) | 1998-12-22 | — | — | US | disclosed |
| EP-0711768-A1 | BENZIMIDAZOLE DERIVATIVE | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-15 | — | — | EP | disclosed |
| US-4810422-A | CARCINOSTATS OF LOW TOXICITY | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1989-03-07 | — | — | US | disclosed |
| EP-0259185-A1 | Bile acid derivatives, their salts and production thereof | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1988-03-09 | — | — | EP | disclosed |