SCHEMBL4289838

SCHEMBL4289838

CCN(CC)Cc1ccc(C(=O)O)cc1

nearest known ligand 0.66

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HDAC8 Q9BY41 1/20 0.66
HDAC6 Q9UBN7 1/20 0.66
ALDH1A1 P00352 2/20 0.61
MEP1B Q16820 2/20 0.59
ALDH2 P05091 1/20 0.58
HRH3 Q9Y5N1 3/20 0.57
ACHE P22303 2/20 0.54
LTA4H P09960 1/20 0.52
TAS2R14 Q9NYV8 2/20 0.49
BCHE P06276 1/20 0.49
RARB P10826 1/20 0.49
TP53 P04637 1/20 0.48
TSHR P16473 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6297059 0.98 HDAC8 (0.64) HDAC8HDAC6ALDH1A1MEP1BALDH2
SCHEMBL19869191 0.89 HDAC8 (0.54) HDAC8HDAC6ALDH1A1MEP1BALDH2
Benzoic Acid SCHEMBL4162737 0.89 MEP1B (0.55) HDAC8HDAC6MEP1BACHELTA4H
SCHEMBL13679679 0.86 HDAC8 (0.68) HDAC8HDAC6ALDH1A1MEP1BALDH2
Terephthalic Acid SCHEMBL27952507 0.85 ALDH1A1 (0.60) ALDH1A1ALDH2RARBTP53TSHR
Terephthalic Acid SCHEMBL8092811 0.85 ALDH1A1 (0.60) ALDH1A1ALDH2RARBTP53TSHR
SCHEMBL1636569 0.85 HRH3 (0.60) HDAC8HDAC6ALDH1A1MEP1BALDH2
SCHEMBL540981 0.84 HRH3 (0.71) HDAC8HDAC6ALDH1A1ALDH2HRH3
SCHEMBL24835162 0.84 ACHE (0.60) ACHELTA4HTAS2R14BCHE
SCHEMBL16187980 0.83 ACHE (0.63) HDAC8HDAC6ALDH1A1HRH3ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112745459-A Concrete viscosity regulator and preparation method thereof 科之杰新材料集团有限公司 2021-05-04 CN claimed
CN-112707670-A Cross-linked concrete viscosity regulator and preparation method thereof 科之杰新材料集团有限公司 2021-04-27 CN claimed
US-4305940-A Benzamides with local anaesthetic and antiarrhythmic activity, salts, and method of preparation thereof and pharmaceutical compositions therefrom B.B.R. BOEHRINGER BIOCHEMIA ROBIN S.P.A. (IT) 1981-12-15 US claimed
EP-3363645-B1 PRETREATMENT OF UV CURED INK UNDER-LAYERS XEROX CORP (US) 2019-10-23 EP disclosed
EP-3375621-A2 TWO COMPONENT INK JETTABLE PRIMER AND INCORPORATION OF ADHESION PROMOTER TO THE INK FOR PRINTING ONTO 3D OBJECTS Xerox Corporation (US) 2018-09-19 EP disclosed
EP-3363645-A1 PRETREATMENT OF UV CURED INK UNDER-LAYERS Xerox Corporation (US) 2018-08-22 EP disclosed
US-10005294-B1 Two component ink jettable primer and incorporation of adhesion promoter to the ink for printing onto 3D objects XEROX CORPORATION (US) 2018-06-26 US disclosed
US-9969185-B1 Pretreatment of UV cured ink under-layers XEROX CORPORATION (US) 2018-05-15 US disclosed
EP-2803504-B1 TIRE BRIDGESTONE CORP (JP) 2018-04-11 EP disclosed
US-9821612-B2 Tire BRIDGESTONE CORPORATION (JP) 2017-11-21 US disclosed
US-9498976-B2 Ultraviolet-curable aqueous ink, ink cartridge, recording apparatus and recording method FUJI XEROX CO., LTD. (JP) 2016-11-22 US disclosed
EP-0813527-A1 6-SUBSTITUTED PYRAZOLO 3,4-d] PYRIMIDIN-4-ONES AND COMPOSITIONS AND METHODS OF USE THEREOF SANOFI PHARMACEUTICALS, INC. (US) 1997-12-29 EP disclosed
US-5696126-A Prodrug esters of phenolic 2-piperidino-1-alkanols PFIZER INC. (US) 1997-12-09 US disclosed
US-5654302-A Prodrug esters of phenolic 2-piperidino-1-alkanols PFIZER INC. (US) 1997-08-05 US disclosed
US-5594007-A Method for treating spinal cord trauma with phenolic 2-piperidino-1-alkanols PFIZER INC. (US) 1997-01-14 US disclosed
WO-1996028429-A1 6-SUBSTITUTED PYRAZOLO [3,4-d] PYRIMIDIN-4-ONES AND COMPOSITIONS AND METHODS OF USE THEREOF SANOFI WINTHROP, INC. (US) 1996-09-19 WO disclosed
US-5455250-A Prodrug esters of phenolic 2-piperidino-1-alkanols PFIZER INC. (US) 1995-10-03 US disclosed
EP-0584192-A1 PRODRUG ESTERS OF PHENOLIC 2-PIPERIDINO-1-ALKANOLS PFIZER INC. (US) 1994-03-02 EP disclosed
CN-1065866-A The prodrug esters of phenol 2-piperidino-(1-position only)-1-alkanol PFIZER (US) 1992-11-04 CN disclosed
WO-1992018502-A1 PRODRUG ESTERS OF PHENOLIC 2-PIPERIDINO-1-ALKANOLS PFIZER INC. (US) 1992-10-29 WO disclosed