Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CDC25A | P30304 | 1/20 | 0.39 |
| ▸ | CDC25B | P30305 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7470522 | 0.85 | MEP1B (0.57) | HDAC8HDAC6ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL5393101 | 0.81 | HDAC8 (0.64) | HDAC8HDAC6ALDH1A1SMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL9837835 | 0.79 | HDAC8 (0.62) | HDAC8HDAC6ALDH1A1POLBHRH3 | |
| SCHEMBL7471752 | 0.79 | SMN1; SMN2 (0.56) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL2771691 | 0.76 | HRH3 (0.52) | HDAC8HDAC6ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL3962189 | 0.75 | CA1 (0.43) | HDAC8ALDH1A1SMN1; SMN2MAPTPOLB | |
| SCHEMBL186794 | 0.74 | CA1 (0.64) | ALDH1A1SMN1; SMN2MAPTPOLBMEN1 | |
| Hydrochloric Acid SCHEMBL9834919 | 0.74 | HRH3 (0.50) | HDAC6ALDH1A1SMN1; SMN2MAPTPOLB | |
| SCHEMBL7462603 | 0.74 | EGFR (0.60) | HDAC8HDAC6ALDH1A1SMN1; SMN2MAPT | |
| Methylene Chloride SCHEMBL29223376 | 0.73 | ALDH1A1 (0.52) | ALDH1A1MAPTCA1CA2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711768-B1 | BENZIMIDAZOLE DERIVATIVE | MITSUI CHEMICALS INC (JP) | 2002-02-13 | — | — | EP | disclosed |
| US-5852011-A | Benzimidazole derivatives | MITSUI CHEMICALS, INC. (JP) | 1998-12-22 | — | — | US | disclosed |
| EP-0711768-A1 | BENZIMIDAZOLE DERIVATIVE | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-15 | — | — | EP | disclosed |