Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.50 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.45 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.41 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.40 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.39 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7458966 | 0.92 | MAPK1 (0.47) | HTTHRH4CNR1CNR2PIK3CD | |
| SCHEMBL7470693 | 0.91 | HTT (0.45) | HTTHRH4NR2F2MEN1MAPT | |
| SCHEMBL7474097 | 0.90 | HRH4 (0.56) | HTTHRH4NR2F2CNR1CNR2 | |
| SCHEMBL7470182 | 0.88 | HTT (0.50) | HTTHRH4NR2F2CNR1CNR2 | |
| SCHEMBL7471116 | 0.88 | HTT (0.52) | HTTHRH4NR2F2CNR1CNR2 | |
| SCHEMBL7466405 | 0.86 | HTT (0.48) | HTTHRH4NR2F2CNR1CNR2 | |
| SCHEMBL7463152 | 0.86 | HTT (0.48) | HTTHRH4NR2F2CNR1CNR2 | |
| SCHEMBL7470615 | 0.86 | HTT (0.50) | HTTHRH4NR2F2CNR1CNR2 | |
| SCHEMBL7469787 | 0.85 | HTT (0.48) | HTTHRH4NR2F2CNR1CNR2 | |
| SCHEMBL7466801 | 0.85 | HTT (0.48) | HTTHRH4NR2F2CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |